Intrauterine contraceptive device versus barrier methods for breast cancer women undergoing postoperative chemotherapy: A randomized controlled trial | ||||
| The Egyptian Journal of Fertility of Sterility | ||||
| Article 2, Volume 19, Issue 1 - Serial Number 11106352, January 2015, Page 11-16 PDF (1.89 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/egyfs.2015.257487 | ||||
 View on SCiNiTO | ||||
| Author | ||||
| Hanan Nabil | ||||
| 3Department of Obstetrics and Gynecology, Faculty of Medicine, Mansura University, Egypt. | ||||
| Abstract | ||||
| Objective: to compare the effectiveness of intrauterine device and the barrier methods of contraception in the form of male condom during the postoperative chemotherapy period in patients with breast cancer at the reproductive age. Study design: A randomized controlled clinical study enrolled married patients, aged ≤ 44 yearswith breast cancer scheduled for chemotherapy. Group (A) (n=51) randomly used intrauterine device and group < br />(B) (n=51) used male condom for contraception. Results: Although patients’ menstrual patterns showed no significant differences at the entry to the study, patients in group (A) showed heavier cycles when evaluated after 3m and again after 6m form the onset of the chemotherapy. The duration of bleeding (mean ±SD) was 7.7±1.7 and 5.6±1.3 in group A and B respectively after 3m and significant changes in the cycle length and the duration of bleeding after 6m had occurred. Likewise, the incidence of genital tract infection was higher in the group using intrauterine device while receiving chemotherapy. Conclusion: While intrauterinecontraceptive device was always considered as the method of choice for most of the malignant patients, this study showed that it is more practical to use the barrier methods at least during the chemotherapy cycles in order to minimize the associated hazards of chemotherapy induced bone marrow depression on the safety of intrauterine device. | ||||
| Keywords | ||||
| Key Words: breast cancer; reproductive age; intrauterine contraceptive device; barrier methods | ||||
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