Protective and ameliorative role of date palm pollen and vitamin C against gastric toxicity induced by bisphenol-A in male albino rat
El-Sayed, M., Abdel-Ghaffar, S., Habib, T., El-Sayed, M. (2022). Protective and ameliorative role of date palm pollen and vitamin C against gastric toxicity induced by bisphenol-A in male albino rat. EKB Journal Management System, 7(3), 183-187. doi: 10.21608/sjsci.2022.157065.1023
Mohamed El-Sayed; Sarry Abdel-Ghaffar; Tito Habib; Mohamed Ali El-Sayed. "Protective and ameliorative role of date palm pollen and vitamin C against gastric toxicity induced by bisphenol-A in male albino rat". EKB Journal Management System, 7, 3, 2022, 183-187. doi: 10.21608/sjsci.2022.157065.1023
El-Sayed, M., Abdel-Ghaffar, S., Habib, T., El-Sayed, M. (2022). 'Protective and ameliorative role of date palm pollen and vitamin C against gastric toxicity induced by bisphenol-A in male albino rat', EKB Journal Management System, 7(3), pp. 183-187. doi: 10.21608/sjsci.2022.157065.1023
El-Sayed, M., Abdel-Ghaffar, S., Habib, T., El-Sayed, M. Protective and ameliorative role of date palm pollen and vitamin C against gastric toxicity induced by bisphenol-A in male albino rat. EKB Journal Management System, 2022; 7(3): 183-187. doi: 10.21608/sjsci.2022.157065.1023

Protective and ameliorative role of date palm pollen and vitamin C against gastric toxicity induced by bisphenol-A in male albino rat

Sohag Journal of Sciences
Volume 7, Issue 3, September 2022, Page 183-187  XML PDF (1.36 MB)
Document Type: Regular Articles
DOI: 10.21608/sjsci.2022.157065.1023
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Authors
Mohamed El-Sayed email 1; Sarry Abdel-Ghaffar2; Tito Habiborcid 3; Mohamed Ali El-Sayed3
1Zoology Department, Faculty of Science, Sohag University, Sohag, Egypt
2Department of Pathology and Clinical pathology, Veterinary medicine Faculty, Assiut University
3Department of Zoology, Faculty of Science, Sohag University, Sohag, 52824, Egypt
Abstract
This study evaluated the protective and ameliorative role of date palm pollen and vitamin C against bisphenol- A ( BPA ) induced gastric structure toxicity in rats. control rats received only food and water, Second group administrated BPA ( 30 mg/kg b.wt. ). Third group was given DPP (100 mg/kg b.wt.).Fourth group was given Vit. C (160 mg/kg b.wt.). Fifth group was given DPP 12 hrs before administration of DPP, while the sixth group was given BPA 12 hrs before administration of BPA. The seventh group was given Vit. C 12 hrs before administration of BPA, whereas the eighth group was given BPA 12 hrs before administration of vit. C. The ninth group was given DPP combined with Vit. C 12 hrs before administration of BPA.BPA induced histopathological changes in the stomach indicated by congestion at the vasculatureand edema of the submucosal layer of the non-glandular part, and congestion of the blood vessels at the muscular layer of the glandular part. However, administration of each DPP and vitamin C before and after BPA, or combined with each other before BPA, restored the normal histological structure of the stomach. So, this study revealed that DPP and Vit. C protected and ameliorated gastric structure against BPA toxicity via their antioxidant activities.
Keywords
Bisphenol-A; gastric tissue; date palm pollen; Vitamin C; male rats
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