Cardiovascular status and metabolic syndrome among young women with polycystic ovarian syndrome in a rural area in Egypt | ||||
The Egyptian Journal of Fertility of Sterility | ||||
Article 2, Volume 16, Issue 2 - Serial Number 11106352, June 2012, Page 13-17 PDF (1.53 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/egyfs.2012.257687 | ||||
View on SCiNiTO | ||||
Author | ||||
Ehsan Refaie, Wael Refaie | ||||
Department of Obstetrics & Gynecology, Mansoura Faculty of Medicine, Mansoura, Egypt | ||||
Abstract | ||||
Objective: To evaluate the cardiovascular status and risk factors among active non smoker young PCOS women, in a rural community in Egypt, with or without features of MS. Materials & Methods: A case control study comprised of 312 PCOS women who were UHFUXLWHGIURPWKH2XWSDWLHQW&OLQLFV0DQVRXUD8QLYHUVLW\+RVSLWDOVIXO¿OOLQJWKH5RWWHUGDPFRQVHQVXVFULWHULDRI3&267KH\FRPSULVHGRIZRPHQZKRIXO¿OOHG WKHGH¿QLWLRQFULWHULDRI06DFFRUGLQJWR1DWLRQDO&KROHVWHURO(GXFDWLRQ3URJUDPDQG WKH$GXOW7UHDWPHQW3DQHO,,,7KHUHPDLQLQJFDVHVGLGQRWIXO¿OOWKHGH¿QLWLRQ criteria (non- MS PCOS). A healthy age-matched control group of 50 women free of 3&26ZHUHDOVRLQFOXGHG$OOFDVHVDQGFRQWUROXQGHUZHQW(&*47FLQWHUYDODQDO\VLV echocardiography for interventricular septum diameter (IVSD) and ejection fraction (EF) estimation, and carotid intima media thickness (cIMT) by ultrasound Doppler study. Results:&DUGLRYDVFXODUDEQRUPDOLWLHVZHUHVLJQL¿FDQWO\KLJKHUDPRQJWKH063&26 FDVHVFRPSDUHGWRQRQ063&26VLJQL¿FDQWSURORQJDWLRQRI47FLQWHUYDO3ZLWK HYLGHQW47GLVSHUVLRQ3VLJQL¿FDQWLQFUHDVHLQ,96'3LQVLJQL¿FDQWGHFUHDVHLQ()DQGVLJQL¿FDQWLQFUHDVHLQF,073LQ3&26FDVHVZLWK062QWKH RWKHUKDQGWKHQRQ063&26FDVHVVKRZHGVLJQL¿FDQWSURORQJDWLRQRI47FLQWHUYDO3 VLJQL¿FDQWLQFUHDVHLQ,96'3VLJQL¿FDQWGHFUHDVHLQ()3DQG VLJQL¿FDQWLQFUHDVHLQF,073ZKHQFRPSDUHGWRWKHKHDOWK\FRQWUROZRPHQ Conclusion: Many cardiovascular risks are frequent and evidence of premature atherosclerosis is existent among young women with PCOS, being even more exaggerated if there is associated MS. Early intervention to ameliorate cardiovascular risks for these cases is an important health care demand. | ||||
Keywords | ||||
Keywords: Polycystic ovary syndrome; metabolic syndrome; cardiovascular risks | ||||
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