Effect of Preoperative Level of Hemoglobin A1C on Early Outcome After Coronary Artery Bypass Graft Surgery | ||||
Zagazig University Medical Journal | ||||
Article 19, Volume 30, Issue 1.3, March and April 2024, Page 155-161 PDF (960.49 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/zumj.2022.157231.2624 | ||||
View on SCiNiTO | ||||
Authors | ||||
Ashraf Hamed Abdelsalam1; Ahmed Mohammed Deebis 2; Amr Hassan Mansour3; Alawab Mohammed Mesallam4; Tamer Mohamed Goda5; Niveen Shafeek Shokry Sakla6; Tamer Salem Alawady 7 | ||||
1Cardiothoracic surgery department, Faculty of Medicine, Zagazig University | ||||
2Cardiothoracic Surgery Department, Faculty of Medicine, Zagazig University, Egypt | ||||
3Department of Cardiothoracic surgery, Zagazig University, Egypt | ||||
4Cardiothoracic Surgery Department, Alahrar Educational Hospital, Zagazig, Egypt | ||||
5Intenal nedicine department,, zagazig university | ||||
6Nephrology Unit-Zagazig University | ||||
7cardiothoracic surgery department, faculty medicine, zagazig university, zagazig, egypt | ||||
Abstract | ||||
Objective: Diabetics represent an increasing proportion of patients undergoing coronary artery bypass graft (CABG). Glycosylated hemoglobin (HbA1C) is a key indicator for glycemic control. The degree of glycemic control is directly reflected in the outcome after CABG. Our study aims to analyze the early outcome concerning preoperative HbA1C levels. Methods: This prospective study evaluated the early outcome of 623 isolated elective CABG patients over 19 months. The patients were divided into group A (347 patients) with HbA1C < 7% and group B (276 patients) with HbA1C ≥ 7%. Postoperative renal failure, myocardial infarction, atrial fibrillation (AF), wound infection, cerebrovascular accidents, and 30-day mortality were recorded. Results: Baseline characteristics showed a non-significant difference between both groups. The mean age of patients in group A was 59.6 years, and in group B it was 59.5 years. The mean graft number was 3.35 and 3.32 for groups A and B, respectively. First-month death was 0.9% in group A and 1.4% in group B without a significant difference. The incidence of AF, superficial wound infection, and other site infections showed a statistically substantial difference between both groups. Conclusion: Increased levels of HbA1c, more than 7%, may be a potential risk factor for postoperative complications with a substantial rise in the risk of wound infections (superficial sternal and non-sternal surgical) and AF. | ||||
Keywords | ||||
Keywords: Glycosylated hemoglobin; HbA1C; CABG; Sternal wound infection | ||||
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