The influence of high responders on the outcome of intracytoplasmic sperm injection | ||||
| The Egyptian Journal of Fertility of Sterility | ||||
| Article 6, Volume 16, Issue 2 - Serial Number 11106352, June 2012, Page 29-32 PDF (1.22 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/egyfs.2012.257781 | ||||
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| Author | ||||
| Ehsan Refaie, Wael Refaie | ||||
| Department of Obstetrics & Gynecology, Mansoura Faculty of Medicine, Mansoura, Egypt | ||||
| Abstract | ||||
| Objective: Evaluate the impact of high number of retrieved oocytes on the outcome of ICSI cycles. Material and methods: A retrospective study performed in Mansoura integrated fertil- ity center. We reviewed 1566 ICSI cycles and compared the patient, cycle features and cycle outcome of ICSI for high responders (> 15 retrieved oocytes corresponding to > 75th percentile) and normal responders (5- 15 oocytes between 25th and 75th percentile). Results: High responders were significantly younger and thinner than the normal respond- ers. The oocyte maturation was significantly lower in high responders. Fertilization rate, Implantation rate and the clinical pregnancy rate revealed significant differences being lower in high responders. Conclusion: High oocyte yield is detrimental to ICSI outcome. It does not only affect the maturation of oocyte but also affects the fertilization, the implantation and the clinical pregnancy rate. | ||||
| Keywords | ||||
| Key word: High responders; ICSI; implantation; pregnancy rate | ||||
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