Silver Nanoparticle Produced by Using Abelmoschus esculentus (L.) Moench Leaves Extract Via Bioreduction Processs as Blood Glucose Nanosensor | ||||
| Egyptian Journal of Chemistry | ||||
| Article 42, Volume 65, Issue 11, November 2022, Page 467-474 PDF (730.1 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2022.74382.3676 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ajeng Kurniati Roddu1; Abdul Wahid Wahab2; Paulina Taba 3; Ahyar Ahmad  4
| ||||
| 1Faculty of Pharmacy, University of East Indonesia, Makassar-Indonesia Jalan. Rappocini Raya, Makassar-Indonesia | ||||
| 2Department of Chemistry, Faculty Mathematics and Natural Science, University of Hasanuddin, Jalan. Perintis Kemerdekaan 90245, Makassar-Indonesia | ||||
| 3Department of Chemistry, Faculty of Mathematics and Natural Sciences, Hasanuddin University | ||||
| 4Chemistry Department, Mathematics and Natural Sciences, Hasanuddin University, Makassar, Indonesia | ||||
| Abstract | ||||
| Silver nanoparticles were produced through bioreduction using Abelmoschus esculentus leaves extract and applied as a blood glucose nano sensor. The biosynthetic reaction produced silver nanoparticles by mixing Abelmoschus esculentus leaves extract and Ag+. The formation of silver nanoparticles was characterized by a color change in the solution from yellow to brown. Silver nanoparticles were analyzed using UV-Vis, FT-IR, PSA, and TEM. Furthermore, the design and testing of blood glucose nanosensors was carried out. The UV-Vis test results showed that the best silver nanoparticles were produced during an incubation period of 6 days with a band gap energy of 2.096 eV. The FT-IR spectrum showed that there had been a bioreduction process as indicated by a decrease in the intensity of the functional groups which were bioreductors. TEM and PSA results showed that silver nanoparticles were spherical and oval in shape with a size of less than 50 nm. The design and application results for the nanosensor showed that silver nanoparticles were in the range of 0.5 mM - 8 mM with a Regression (R) of 0.9494. The detection limit of the silver nanoparticle sensor was at a concentration of 1.68 mM with a sensitivity of 3.27 A. mM-1. mm-2. The glucose level contained in blood samples with silver nanoparticle sensors was 93.05 mg / dL with a measurement difference of 1.95% when compared to Automated Analyzed Clinical Chemistry. | ||||
| Keywords | ||||
| silver nanoparticles; bioreduction; nanosensors; blood glucose; Abelmoschus esculentus; detection | ||||
|
Statistics Article View: 228 PDF Download: 151 |
||||
