Relationship between Serum IgE and Airway Responsiveness in Adults with Asthma | ||||
Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology | ||||
Article 7, Volume 14, Issue 2, December 2022, Page 53-56 PDF (392.54 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/eajbsc.2022.260470 | ||||
View on SCiNiTO | ||||
Authors | ||||
Mazen Almehmadi1; Saad Alghamdi2; Mashael Kelantan3; Suleman Khan4; Mahdi H. Alsugoor5; Samiyah Tasleem6; Farkad Bantun7; Ahad Amer Alsaiari8 | ||||
1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia | ||||
2Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah 21912, Saudi Arabia. | ||||
3Department of Preventive Medicine & Public Health, Hera General Hospital, Makkah, Saudi Arabia | ||||
4Department of Health and Biological Sciences Abasyn University Peshawar, Khyber Pakhtunkhwa-25130-Pakistan | ||||
5Department of Emergency Medical Services, Faculty of Health Sciences, AlQunfudah, Umm Al-Qura University, Makkah 21912, Saudi Arabia. | ||||
6Department of Microbiology, University of Karachi-75270-Pakistan. | ||||
7Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah 21912, Saudi Arabia. | ||||
8Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia. | ||||
Abstract | ||||
Several cell types and a wide variety of inflammatory mediators are involved in the chronic airway inflammation that characterizes asthma. The study aims to uncover a link between high serum immunoglobulin E IgE levels and childhood asthma. This cross-sectional study was conducted from March to July 2022 at Khyber Teaching Hospital Peshawar, Pakistan. Asthma patients traveling to the clinic's out-of-the-way chest medication branch were given a clear explanation of the review's goal, its system, and its security measures. This study included 65 patients. This study lists demographic, clinical, and useful characteristics. The research review included 18–60-year-old patients. 40 (66.67%) of our 60 patients were men, and 20 (33.33%) were women. Out of 60 cases, 56.67% had severe asthma. The researchers concluded that the serum levels of immunoglobulin E in asthmatics were much higher than those in normal patients. The severity of the patient's asthma was correlated with an increase in their IgE levels, on average. | ||||
Keywords | ||||
Asthma; IgE; bronchi | ||||
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