Correlation between Hyperuricemia and Severity of Coronary Artery Disease Detected by Coronary Angiography in Men and Women
Madbouly, M., Boghdady, A., Abd El Hady, Y., Abd El Meguid, K. (2022). Correlation between Hyperuricemia and Severity of Coronary Artery Disease Detected by Coronary Angiography in Men and Women. EKB Journal Management System, 3(4), 7-19. doi: 10.21608/ejmr.2022.263555
Mohammed Abd El Shakour Madbouly; Ahmed Mohammed Boghdady; Yasser Ahmed Abd El Hady; Khaled Refaat Abd El Meguid. "Correlation between Hyperuricemia and Severity of Coronary Artery Disease Detected by Coronary Angiography in Men and Women". EKB Journal Management System, 3, 4, 2022, 7-19. doi: 10.21608/ejmr.2022.263555
Madbouly, M., Boghdady, A., Abd El Hady, Y., Abd El Meguid, K. (2022). 'Correlation between Hyperuricemia and Severity of Coronary Artery Disease Detected by Coronary Angiography in Men and Women', EKB Journal Management System, 3(4), pp. 7-19. doi: 10.21608/ejmr.2022.263555
Madbouly, M., Boghdady, A., Abd El Hady, Y., Abd El Meguid, K. Correlation between Hyperuricemia and Severity of Coronary Artery Disease Detected by Coronary Angiography in Men and Women. EKB Journal Management System, 2022; 3(4): 7-19. doi: 10.21608/ejmr.2022.263555

Correlation between Hyperuricemia and Severity of Coronary Artery Disease Detected by Coronary Angiography in Men and Women

Egyptian Journal of Medical Research
Volume 3, Issue 4, October 2022, Page 7-19  XML PDF (429 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2022.263555
View on SCiNiTO View on SCiNiTO
Authors
Mohammed Abd El Shakour Madbouly1; Ahmed Mohammed Boghdady2; Yasser Ahmed Abd El Hady1; Khaled Refaat Abd El Meguid1
1Cardiology department, Faculty of Medicine, Beni-Seuf University, Egypt
2Internal medicine department, Faculty of Medicine, Sohag University, Egypt
Abstract
The association between serum uric acid and ischemic heart disease remains controversial and serum uric acid has not yet been established as cardiovascular risk factor. Our objective was to study the association of serum uric acid level with angiographic severity of coronary artery disease in males and females with ischemic heart disease. This observational study was conducted on two hundred patients divided into one hundred male patient, subdivided into fifty patient with elevated SUA and fifty patient with normal SUA and one hundred female patient subdivided into fifty patient with elevated SUA and fifty patient with normal SUA underwent coronary angiography for detection of CAD in cath lab unit of cardiology department of Beni-Suef and Sohag university. The severity of CAD was assessed on the basis of Gensini score and clinical vessel score. For all groups, conventional risk factors, levels of serum uric acid, and other biochemical markers were assessed.
Keywords
Serum uric acid; Coronary artery disease; Gensini score; Coronary angiography
References
  1. Majdzadeh, R., et al., Iran’s approach to knowledge translation. 2009. 38(Suppl 1): p. 58-62.
  2. Okura, T., et al., Elevated serum uric acid is an independent predictor for cardiovascular events in patients with severe coronary artery stenosis. 2009. 73(5): p. 885-891.
  3. Sinan Deveci, O., et al., The association between serum uric acid level and coronary artery disease. 2010. 64(7): p. 900-907.
  4. Becker, M.A. and M.J.R.D.C. Jolly, Hyperuricemia and associated diseases. 2006. 32(2): p. 275-293.
  5. Nunes, J.P.L. and J.C.J.P.o. Silva, Systemic correlates of angiographic coronary artery disease. 2009. 4(1): p. e4322.
  6. Krishnan, E., et al., Hyperuricemia and the risk for subclinical coronary atherosclerosis-data from a prospective observational cohort study. 2011. 13(2): p. 1-8.
  7. Goodarzynejad, H., et al., Hyperuricemia and the presence and severity of coronary artery disease. 2010. 41(1): p. 40-45.
  8. Guo, L.-x., et al., Urinary albumin excretion rate is correlated with severity of coronary artery disease in elderly type 2 diabetic patients. 2012. 125(23): p. 4181-4184.
  9. Fox, K., et al., The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. 2006. 27(11): p. 1341-1381.
  10. Anderson, J.L., et al., Management of patients with peripheral artery disease (compilation of 2005 and 2011 accf/aha guideline recommendations) a report of the american college of cardiology foundation/american heart association task force on practice guidelines. 2013. 61(14): p. 1555-1570.
  11. Guidelines, E.C.f.P., et al., Third universal definition of myocardial infarction. 2012. 60(16): p. 1581-1598.
  12. Verdecchia, P., et al., Usual versus tight control of systolic blood pressure in non-diabetic patients with hypertension (Cardio-Sis): an open-label randomised trial. 2009. 374(9689): p. 525-533.
  13. Mellitus, D.J.D.c., Diagnosis and classification of diabetes mellitus. 2005. 28(S37): p. S5-S10.
  14. Luk, A.J. and P.A.J.A.J.M.C. Simkin, Epidemiology of hyperuricemia and gout. 2005. 11(15 Suppl): p. S435-S442.
  15. Reiner, Ž.J.E.J.o.C.P. and Rehabilitation, New ESC/EAS Guidelines for the management of dyslipidaemias− any controversies behind the consensus? 2011. 18(5): p. 724-727.
  16. de Oliveira, E.P., R.C.J.D. Burini, and m. syndrome, High plasma uric acid concentration: causes and consequences. 2012. 4(1): p. 1-7.
  17. Poirier, P., et al., Cardiovascular evaluation and management of severely obese patients undergoing surgery: a science advisory from the American Heart Association. 2009. 120(1): p. 86-95.
  18. Mene, P. and G.J.J.o.h. Punzo, Uric acid: bystander or culprit in hypertension and progressive renal disease? 2008. 26(11): p. 2085-2092.
  19. Gensini, G.G.J.A.J.c., A more meaningful scoring system for determining the severity of coronary heart disease. 1983. 51: p. 606.
  20. Duran, M., et al., High levels of serum uric acid predict severity of coronary artery disease in patients with acute coronary syndrome. 2012. 63(6): p. 448-452.
  21. Qureshi, A.E., S. Hameed, and A.J.P.j.o.m.s. Noeman, Relationship of serum uric acid level and angiographic severity of coronary artery disease in male patients with acute coronary syndrome. 2013. 29(5): p. 1137.
  22. Akanda, M., et al., Serum uric acid and its association with coronary artery disease. 2012. 5(1): p. 12-17.
  23. Tuttle, K.R., R.A. Short, and R.J.J.A.J.o.C. Johnson, Sex differences in uric acid and risk factors for coronary artery disease. 2001. 87(12): p. 1411-1414.
  24. Petersen, T.S., et al., Uric acid in patients with angiographically documented coronary heart disease. 2006. 61(5): p. 525-529.
Statistics
Article View: 184
PDF Download: 165