Preschool wheeze among a retrospective cohort of Egyptian children
El-Sayed, Z., El-Owaidy, R., Wassif, G., Al-Gaweesh, R., Shousha, G. (2022). Preschool wheeze among a retrospective cohort of Egyptian children. EKB Journal Management System, 20(2), 61-68. doi: 10.21608/ejpa.2022.264469
Zeinab A. El-Sayed; Rasha El-Owaidy; Ghada Wassif; Roba Al-Gaweesh; Ghada Shousha. "Preschool wheeze among a retrospective cohort of Egyptian children". EKB Journal Management System, 20, 2, 2022, 61-68. doi: 10.21608/ejpa.2022.264469
El-Sayed, Z., El-Owaidy, R., Wassif, G., Al-Gaweesh, R., Shousha, G. (2022). 'Preschool wheeze among a retrospective cohort of Egyptian children', EKB Journal Management System, 20(2), pp. 61-68. doi: 10.21608/ejpa.2022.264469
El-Sayed, Z., El-Owaidy, R., Wassif, G., Al-Gaweesh, R., Shousha, G. Preschool wheeze among a retrospective cohort of Egyptian children. EKB Journal Management System, 2022; 20(2): 61-68. doi: 10.21608/ejpa.2022.264469

Preschool wheeze among a retrospective cohort of Egyptian children

The Egyptian Journal of Pediatric Allergy and Immunology
Article 3, Volume 20, Issue 2, October 2022, Page 61-68  XML PDF (325.18 K)
Document Type: Original Article
DOI: 10.21608/ejpa.2022.264469
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Authors
Zeinab A. El-Sayed1; Rasha El-Owaidyorcid 2; Ghada Wassif3; Roba Al-Gaweesh4; Ghada Shousha email 4
1Pediatric allergy and immunology unit, Children's Hospital, Ain Shams University
2MD, PhD. Lecturer of Pediatrics and Pediatric Allergy and Immunology, Ain-Shams University, Egypt. Member, ESPAI, WAO, EAACI, ESID, ASID
3Department of Community Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt
4Pediatrics Allergy, Immunology and Rheumatology Unit, Children’s Hospital, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Abstract
Background: Prevalence of recurrent wheeze in the preschool age was reported to affect one third of children in the developed world, with even more frequency and severity in the developing countries. Epidemiological studies on this subject in Egypt are lacking. We sought to investigate the frequency and different phenotypes of preschool wheeze (PSW) among a group of Egyptian children and their relation to different risk factors. Methods: A retrospective cohort study was conducted on 1209 children, aged 6-10 years, recruited from the Outpatients’ Clinics of Ain Shams University Hospitals from March 2019 to March 2021. Children with underlying chronic disease or suspected to be immunodeficient were excluded. The main study tool was a survey composed of 30 questions and presented to the parent/caregiver via direct interviewing by the investigator and included sociodemographic data details of wheezing episodes before the age of 6, wheezing risk factors and comorbidities. Skin prick test (SPT) was done for the prolonged early, persistent early and late onset wheezers, while pulmonary function tests were done for the currently asthmatics patients . Results: History of PSW was positive in 298/1209 (24.6%) of the participants. According to the onset, duration and course of wheezes, preschool wheezers were classified as transient wheezers (10.4%), prolonged early wheezers (3.9%), late onset wheezers (3.2%) and persistent wheezers (7.1%) relevant to the whole cohort. Fifty percent of PSW were multi-trigger wheeze while 39.3% were episodic viral wheeze. Twenty-five patients out of 148 wheezers (16.9%) who underwent SPT were found to be atopic. Conclusion: PSW is commonly reported among Egyptian children, paralleling international reports with transient and persistent early wheezing being the most common phenotypes in Egypt.
Keywords
Preschool wheezes; transient; persistent; Children
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