Role of Sonoelastography in Evaluation of Liver Fibrosis: Review Article | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 222, Volume 89, Issue 1, October 2022, Page 5539-5543 PDF (555.36 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2022.265277 | ||||
 View on SCiNiTO | ||||
| Author | ||||
Omar Ahmed Abdellatif Ahmed 
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| Abstract | ||||
| Background: Liver parenchymal cells, non-parenchymal liver cells, and infiltrating immune cells all play roles in the development and regression of fibrosis. Hepatocyte mortality through chronic causes such apoptosis, necrosis, or necroptosis is essential. Death of cells activates inflammatory and pro-fibrogenic pathways in non-parenchymal cells and invading immune cells, which in turn triggers fibrosis advancement but may also contribute to fibrosis resolution. Patients with hepatitis C have made elastography's usefulness in the diagnosis of fibrosis a priority. Traditional treatment relied heavily on interferon injections, which can have serious adverse effects. Objective: Assessment of possible role ofsonoelastography in evaluation of liver fibrosis. Methods: Mean Platelet Volume, Pediatrics, and Idiopathic Thrombocytopenic were all looked for in PubMed, Google scholar, and Science direct. References from relevant literature were also evaluated by the authors, but only the most recent or complete study from December 2003 to February 2022 was included. Due to the lack of sources for translation, documents in languages other than English have been ruled out. Papers that did not fall under the purview of major scientific investigations, such as unpublished manuscripts, oral presentations, conference abstracts, and dissertations, were omitted. Conclusion: Patients with chronic liver illness have an alternative in sonoelastography that is safe, noninvasive, and accurate for assessing fibrosis. | ||||
| Keywords | ||||
| Sonoelastography; Ultrasound; Hepatitis C; Liver fibrosis | ||||
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