Comparison between Antimicrobial Photodynamic Therapy and Injectable Platelet Rich Fibrin as an adjunct to Non-Surgical Periodontal Treatment (A Randomized Controlled Clinical Trial with Microbiological Assessment)

elarif, abdelrahman; Hussein, Radwa; El-khazragy, nashwa; Kheir El Din, Nevine

doi:10.21608/edj.2022.146616.2170

	Comparison between Antimicrobial Photodynamic Therapy and Injectable Platelet Rich Fibrin as an adjunct to Non-Surgical Periodontal Treatment (A Randomized Controlled Clinical Trial with Microbiological Assessment)
Egyptian Dental Journal
Article 7, Volume 68, Issue 4 - Serial Number 3, October 2022, Page 3273-3283 PDF (812.17 K)
Document Type: Original Article
DOI: 10.21608/edj.2022.146616.2170
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Authors
abdelrahman elarif ¹; Radwa Hussein ²; nashwa El-khazragy ³; Nevine Kheir El Din ⁴
¹Teaching Assistant at Department of Oral Medicine and Periodontology, Faculty of Dentistry, Future university, Cairo, Egypt. Master Candidate at Department of Oral Medicine, Periodontology, Oral Diagnosis and Radiology Department, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
²Lecturer of Oral Medicine and Periodontology, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
³Prof of Clinical Pathology and Hematology, Faculty of Medicine, Ain Shams University
⁴Head of Department of Oral Medicine and Periodontology, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
Abstract
Background: The aim of this study was to compare the efficacy of injectable form of PRF to antimicrobial photo dynamic therapy as an adjunctive treatment to non-surgical periodontal therapy in patients with stage III grade B periodontitis in terms of clinical improvement and antimicrobial ability. Subjects and Methods: 39 patients of each gender with age vary from 30 to 60 years diagnosed with stage III grade B periodontitis. The patients were divided randomly into three groups. (Group I) 13 patients treated by SRP (scaling and root planning) with application of i-PRF, (Group II) 13 patients treated by SRP with application of 940 nm diode laser and Indocyanine green (ICG), (Group III) treated by SRP alone as a control group . Clinical parameters such as GI (gingival index), PI (plaque index), CAL (clinical attachment level) and PD (probing depth) were recorded preoperatively and 3 months post operatively. Site-specific measure of bactericidal effect against Pg preoperative, 1 week postoperative and 1 month postoperative for all groups. Results: group I who receiving i-PRF resulted in a significant decrease in the percentage of Pg at the end of 1 month when compared to the other groups. Comparison of clinical parameters revealed significant differences in patients treated with aPDT in relation to GI, and CAL while i-PRF group , was better in PD at the end of the study period. Conclusion: i-PRF and aPDT may enhance the potential benefits of SRP in periodontitis patients and can be used as an adjunct to nonsurgical periodontal therapy.
Keywords
Stage III Grade B periodontitis; Photodynamic therapy; i-PRF; Porphyromonas gingivalis


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