Comparison of Serum Calcium Level in Preeclamptic and Normotensive Pregnant Women in Ekiti State, Nigeria
Adejube, F., Adebayo, A., Adejube, C., Olaleye, O., Olaleye, A. (2023). Comparison of Serum Calcium Level in Preeclamptic and Normotensive Pregnant Women in Ekiti State, Nigeria. EKB Journal Management System, 6(1), 384-396. doi: 10.21608/svuijm.2022.155299.1371
Francis Bamijoko Adejube; Adeniyi Augustine Adebayo; Caroline Oluseyi Adejube; Omolara Adepate Olaleye; Abiola Olukayode Olaleye. "Comparison of Serum Calcium Level in Preeclamptic and Normotensive Pregnant Women in Ekiti State, Nigeria". EKB Journal Management System, 6, 1, 2023, 384-396. doi: 10.21608/svuijm.2022.155299.1371
Adejube, F., Adebayo, A., Adejube, C., Olaleye, O., Olaleye, A. (2023). 'Comparison of Serum Calcium Level in Preeclamptic and Normotensive Pregnant Women in Ekiti State, Nigeria', EKB Journal Management System, 6(1), pp. 384-396. doi: 10.21608/svuijm.2022.155299.1371
Adejube, F., Adebayo, A., Adejube, C., Olaleye, O., Olaleye, A. Comparison of Serum Calcium Level in Preeclamptic and Normotensive Pregnant Women in Ekiti State, Nigeria. EKB Journal Management System, 2023; 6(1): 384-396. doi: 10.21608/svuijm.2022.155299.1371

Comparison of Serum Calcium Level in Preeclamptic and Normotensive Pregnant Women in Ekiti State, Nigeria

SVU-International Journal of Medical Sciences
Article 39, Volume 6, Issue 1, January 2023, Page 384-396  XML PDF (291.34 K)
Document Type: Original research articles
DOI: 10.21608/svuijm.2022.155299.1371
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Authors
Francis Bamijoko Adejube1; Adeniyi Augustine Adebayo1; Caroline Oluseyi Adejube1; Omolara Adepate Olaleye2; Abiola Olukayode Olaleye email 3
1Federal Teaching Hospital. Ido Ekiti, Nigeria.
2National Hospital, Abuja, Nigeria
3Department of Community Health, Obafemi Awolowo University Teaching Hospitals Complex, Ile Ife, Nigeria.
Abstract
Background: Pre-eclampsia is often referred to as disease of theories as the precise factors involved in its pathogenesis are unclear. While alterations in calcium metabolism have been linked with preeclampsia, the role of calcium in the development of the disease remains uncertain.  
Objectives: This study aimed to compare the clinical features and serum calcium levels of pre-eclamptic women with normotensive controls.
Patients and methods: The study was a case-control study among patients with pre-eclampsia and healthy normotensive women.
Results: Ninety-five preeclamptic patients and 95 matched controls participated in the study. More than half (61.1%) of the pre-eclamptic women were unbooked while only about one-third (30.5%) of the normotensive women were unbooked (P<0.001). Pre-eclamptic women had significantly shorter duration of cohabitation with biological fathers of their foetuses than the normotensive controls. Pre-eclamptic patients were thrice more likely to have family history of hypertension than the control group (14.7% vs 4.2% P=0.013). Similarly, the mean serum calcium levels were statistically significantly lower in preeclamptic patients (1.87± 0.27 mmol/L) compared to the pregnant normotensive controls (2.33±0.28 mmol/L).
Conclusion: Serum calcium levels were significantly lower in pre-eclamptic women compared to the normotensive controls in the study.
Keywords
Serum calcium; Pre-eclampsia; Pregnant women
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