Evaluating the Safety and Efficacy of the traditional use of Turmeric powder as Antihypertensive in Elderly | ||||
NILES journal for Geriatric and Gerontology | ||||
Article 6, Volume 6, Issue 1, January 2023, Page 76-88 PDF (294.52 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/niles.2023.266985 | ||||
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Authors | ||||
Amany Mohamed Basuny* 1, 2; Ibrahim Taha Ibrahim Badawy* 3; Sayed Ali Galal Ali* 2; Ali Mohammed Abdelgawwad Ali* 2 | ||||
1Biochemistry Department, Faculty of Agriculture, Beni Suef University,Egypt. | ||||
2Elderly Nutrition Department -National Institute of Longevity Elderly Sciences. Beni-Suef University, Egypt | ||||
3Biochemistry Department Faculty of Pharmacy - Beni-Suef University, Egypt | ||||
Abstract | ||||
Background: The Curcuma genus has a long history of medicinal applications. Curcuma longa L. (Turmeric) is the most popular cultivated plant.. Curcumin, a polyphenolic yellow substance, is the major constituent of tumeric .Many studies have been done on curcumin and this substance has a variety of effects Carried out on animals. . Curcumin reduced hyperlipidemia and insulin resistance. The current study aimed to measuring this effect on humans. Objective: To assess the effects and safety of taking turmeric powder as antihypertensive agent in elderly. Design: Prospective, observational study. All subjects were selected from Beni Suef University Hospital. The current study includes hypertensive patients with age above 50 years old classified into 2 groups. Group I: Normal control group consists of healthy volunteers. Group II: Hypertensive group includes hypertensive patients. Each group includes 20 subjects (n=20) divided into ( male and female) subjects. In the current study, each group was taken a specific dose of turmeric powder for 8 weeks treatment. Results: The present study revealed that a significant reduction in readings of systolic and diastolic blood pressure had happened for patients who took turmeric powder for two months. As well as a reduction in serum lipid profile including TG, cholesterol, HDL and LDL significantly over a p value of 0.05 or less (p ≤ 0.05) when compared to healthy group. Conclusion: Our data support previous research, suggesting that turmeric powder intake engenders hypotensive and lipid-lowering effects. | ||||
Keywords | ||||
turmeric powder; hypertensive patients; lipid profile; phenolic compounds; curcumin | ||||
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