Association of DEXA with EDX in Evaluation of Inorganic Bone Components After Application of Nano bone For Repair of Bone Defect | ||||
| Al-Azhar Assiut Dental Journal | ||||
| Article 5, Volume 5, Issue 2, October 2022, Page 177-191 PDF (3.26 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/aadj.2022.267279 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Nehad A Ahmad  1; Naglaa Elkilania2
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| 1Department of Oral and Dental Biology, Faculty of Dental Medicine, Al-Azhar University, Cairo (girls), Egypt. | ||||
| 2Department of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology, Faculty of Dental Medicine, Al-Azhar University, Cairo (girls), Egypt. | ||||
| Abstract | ||||
| Aim: The aim of this study is to correlate DEXA and EDX in assessment the variations in chemical composition in terms of the main elements comprising the bone mineral {calcium (Ca), and phosphorus (P)} after application of Nano bone for Repair of bone defect. Subjects and Methods: A bone drill defect was created in the right tibia (two holes in each tibia) of 48 rabbits; upper hole was left empty while the lower hole was packed with NanoBone. 24 animals were sacrificed 2 weeks after surgery; the remaining animals were sacrificed after 4 weeks. Half of the bone specimens prepared for the routine laboratory processing, histological and histomorphometric, while The remaining specimens were scanned by Dual-energy X-ray absorptiometry (DEXA) for bone mineral density measurement and then used for bone mineral composition determination by Energy Dispersive X-ray Analyses (EDX). The measurements of DEXA and EDX have been compared after that, data were submitted to ANOVA and Tukey’s test. Results: DEXA showed a strong positive correlation with EDX and histological analysis. Conclusion: Energy-dispersive X-ray microanalysis (EDX) is a useful quantitative tool for the analysis of Ca and P in bone in a non-invasive way. | ||||
| Keywords | ||||
| Nano bone; DEXA; EDX; Rabbits; bone mineral | ||||
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