Potential Effect of a Novel Composite (Calcium Carbonate Nanoparticles/ Silver Nanoparticles/Advanced-Platelet Rich Fibrin) on Healing of Critical Bone Defect in Rabbits: Radiographic Evaluation | ||||
| Journal of Current Veterinary Research | ||||
| Volume 4, Issue 2, October 2022, Page 104-112 PDF (1.55 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jcvr.2022.267518 | ||||
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| Authors | ||||
Mohamed Abd Elkawi  ; Shaaban M. Gadallah; Tarek N. Misk; Ahmed M. Sharshar
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| Department of Surgery, Radiology and Anesthesiology, Faculty of Veterinary Medicine, University of Sadat City. | ||||
| Abstract | ||||
| The aim of the present study was to evaluate the efficacy of calcium carbonate nanoparticles (CCNPs)/Silver nanoparticles (Ag NPs)/Advanced-PRF composite to induce new bone formation and accelerate bone regeneration when be used to fill an experimentally critical defect in radial bone of rabbits. Twenty-four adult apparently healthy New Zealand white rabbits aged from 5-to 6 months and weighing 3.5 ± 0.5 kg were used in this study and were divided into two groups, group A: was left empty as a control. Group B: we used CCNPs/AgNPs/A-PRF composite. During observation, period rabbits were observed clinically and radiographically at 2,4,8,12 weeks post-operation. Results: the radiographic finding showed a great significant difference between the two groups and the CCNPs/AgNPs/A-PRF composite could make complete healing at the end of the observation period. Conclusion: radiographical studies revealed that CCNPs/AgNPs/A-PRF composite has exalted efficacy to induce new bone formation. | ||||
| Keywords | ||||
| AgNPs; A-PRF; Bone healing; CCNPs and Nano particles | ||||
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