Fat Versus Hyaluronic Acid Injection Laryngoplasty for Unilateral Vocal Fold Paralysis: Efficacy and Results
Sheikhany, A., Abdel moniem, Y., El Sharkawy, L., El-Antably, A., algarf, T. (2022). Fat Versus Hyaluronic Acid Injection Laryngoplasty for Unilateral Vocal Fold Paralysis: Efficacy and Results. EKB Journal Management System, 23(23), 1-9. doi: 10.21608/ejentas.2022.133185.1504
Aya Raouf Sheikhany; Youssef Mohamed Abdel moniem; Louay El Sharkawy; Adel El-Antably; tareq muhammad algarf. "Fat Versus Hyaluronic Acid Injection Laryngoplasty for Unilateral Vocal Fold Paralysis: Efficacy and Results". EKB Journal Management System, 23, 23, 2022, 1-9. doi: 10.21608/ejentas.2022.133185.1504
Sheikhany, A., Abdel moniem, Y., El Sharkawy, L., El-Antably, A., algarf, T. (2022). 'Fat Versus Hyaluronic Acid Injection Laryngoplasty for Unilateral Vocal Fold Paralysis: Efficacy and Results', EKB Journal Management System, 23(23), pp. 1-9. doi: 10.21608/ejentas.2022.133185.1504
Sheikhany, A., Abdel moniem, Y., El Sharkawy, L., El-Antably, A., algarf, T. Fat Versus Hyaluronic Acid Injection Laryngoplasty for Unilateral Vocal Fold Paralysis: Efficacy and Results. EKB Journal Management System, 2022; 23(23): 1-9. doi: 10.21608/ejentas.2022.133185.1504

Fat Versus Hyaluronic Acid Injection Laryngoplasty for Unilateral Vocal Fold Paralysis: Efficacy and Results

Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Article 45, Volume 23, Issue 23, January 2022, Page 1-9  XML PDF (643.11 K)
Document Type: Original Article
DOI: 10.21608/ejentas.2022.133185.1504
View on SCiNiTO View on SCiNiTO
Authors
Aya Raouf Sheikhany1; Youssef Mohamed Abdel moniem email orcid 2; Louay El Sharkawy3; Adel El-Antablyorcid 4; tareq muhammad algarf3
1Cairo University
2Otorhinolaryngology, faculty of medicine, cairo University, Egypt
3otorhinolaryngology, faculty of medicine, cairo university
4Department of otorhinolaryngology, Facuty of Medicine, Cairo University
Abstract
Objectives: To compare the use of autologous fat versus hyaluronic acid in injection laryngoplasty for unilateral vocal fold paralysis. The efficacy of the materials regarding voice outcomes (voice handicap index, computerized speech lab) and duration will be statistically analyzed.
Patients and Methods: A prospective study conducted on 38 randomly selected patients with unilateral vocal fold paralysis presented to ORL outpatient clinic at faculty of medicine – Cairo University randomized to receive either hyaluronic acid (HA) perfecta deep® group A and autologus fat for group B. Postoperative evaluations were made based on Auditory Perceptual Assessment of Voice (APA), Computerized Speech Lab (CSL), jitter, shimmer, noise to harmonic ratio, patient satisfaction, phonatory gap and the need for another injection.
Results: One month postoperatively, both groups showed significant improvement in CSL, APA and phonatory gap while six months postoperatively there was significant improvement in favor of group B. No serious adverse events were observed. 18 patients had been re-injected in group A while only 5 had been re-injected in group B due to insufficient voice.
Conclusion: No side-effects were found for either hyaluronic acid or fat groups after injection. Both treatments after one month resulted in significantly improved voice as rated by the patients and significantly improved glottal closure. Resorption was noted for both substances, but mainly for hyaluronic acid/treatment.
Keywords
Autologous fat; Hoarseness; Hyaluronic acid; Injection laryngoplasty; Vocal fold paralysis
Statistics
Article View: 208
PDF Download: 469