Green Synthesis of Silver NPs based on Arenga engleri leaves extract: Characterization and in-vitro Helicobacter pylori activity
Mahmoud, A., El Raey, M., Emam, M., Abdel–Rahman, A., Zayed, I. (2023). Green Synthesis of Silver NPs based on Arenga engleri leaves extract: Characterization and in-vitro Helicobacter pylori activity. EKB Journal Management System, 66(7), 509-516. doi: 10.21608/ejchem.2022.93919.4423
Amira B. Mahmoud; Mohamed A. El Raey; Mahmoud Emam; Adel A.H. Abdel–Rahman; Ibrahim F. Zayed. "Green Synthesis of Silver NPs based on Arenga engleri leaves extract: Characterization and in-vitro Helicobacter pylori activity". EKB Journal Management System, 66, 7, 2023, 509-516. doi: 10.21608/ejchem.2022.93919.4423
Mahmoud, A., El Raey, M., Emam, M., Abdel–Rahman, A., Zayed, I. (2023). 'Green Synthesis of Silver NPs based on Arenga engleri leaves extract: Characterization and in-vitro Helicobacter pylori activity', EKB Journal Management System, 66(7), pp. 509-516. doi: 10.21608/ejchem.2022.93919.4423
Mahmoud, A., El Raey, M., Emam, M., Abdel–Rahman, A., Zayed, I. Green Synthesis of Silver NPs based on Arenga engleri leaves extract: Characterization and in-vitro Helicobacter pylori activity. EKB Journal Management System, 2023; 66(7): 509-516. doi: 10.21608/ejchem.2022.93919.4423

Green Synthesis of Silver NPs based on Arenga engleri leaves extract: Characterization and in-vitro Helicobacter pylori activity

Egyptian Journal of Chemistry
Volume 66, Issue 7, July 2023, Page 509-516  XML PDF (945.26 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2022.93919.4423
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Authors
Amira B. Mahmoud1; Mohamed A. El Raey2; Mahmoud Emam2, 3; Adel A.H. Abdel–Rahman1; Ibrahim F. Zayed email 1
1Chemistry Department, Faculty of Science, Menoufia University, Egypt
2Phytochemistry and Plant Systematics Department, National Research Centre, Dokki, Giza 12622, Egypt
33College of Pharmaceutical Science & Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China
Abstract
Globally, the infection with Helicobacter pylori (H. pylori) considered the most prevalent issue that causes chronic inflammation of the stomach. In this study, the phytochemical investigation of Arenga engleri (family Arecaceae) leaves extract that used to prepare the AgNPs and examined for their potential activity against H. pylori. The phytochemical results revealed the presence of different phenolic contents depending on the preliminary phytochemical screening, TPC and TFC measurements, and HPLC profiling. Besides, the percent of unsaturated and saturated fatty acids were 51.39 % and 31.47 %, respectively, based on GC/MS analysis. The as- prepared AgNPs were characterized by using UV-Vis spectroscopy, IR spectroscopy, TEM, and Zeta potential analyses. The synthesized AgNPs displayed promising anti H. pylori with MIC = 7.81 µg/mL, while the A. engleri extract showed weak activity with MIC = 500 µg/mL compared with clarithromycin MIC of 1.95 µg/mL after 3 days of incubation. In conclusion, the acids, phenolic, and flavonoid contents of A. engleri extract was used as capping agents to prepare simple, low-cost, and effective AgNPs with a particle size range of 10-26 nm that explained their high penetration towards the bacterial cell of H. pylori and destroyed it
Keywords
Arenga engleri; GC/MS; HPLC; plant extract; Nano particles; phytochemical study
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