Validity of Modified Vienna-CATS Score for Prediction of Venous Thromboembolism in Egyptian Cancer Cases
El-sayed, H., Ebrahim, M., Ghoneim, H., Elagdar, M., Selim, T. (2022). Validity of Modified Vienna-CATS Score for Prediction of Venous Thromboembolism in Egyptian Cancer Cases. EKB Journal Management System, 89(2), 6831-6838. doi: 10.21608/ejhm.2022.270820
Hanaa Ali El-sayed; Mohamed Awad Ebrahim; Hayam Rashad Ghoneim; Mohammed Ahmed Mohammed Abdallah Elagdar; Tarek El-sayed Selim. "Validity of Modified Vienna-CATS Score for Prediction of Venous Thromboembolism in Egyptian Cancer Cases". EKB Journal Management System, 89, 2, 2022, 6831-6838. doi: 10.21608/ejhm.2022.270820
El-sayed, H., Ebrahim, M., Ghoneim, H., Elagdar, M., Selim, T. (2022). 'Validity of Modified Vienna-CATS Score for Prediction of Venous Thromboembolism in Egyptian Cancer Cases', EKB Journal Management System, 89(2), pp. 6831-6838. doi: 10.21608/ejhm.2022.270820
El-sayed, H., Ebrahim, M., Ghoneim, H., Elagdar, M., Selim, T. Validity of Modified Vienna-CATS Score for Prediction of Venous Thromboembolism in Egyptian Cancer Cases. EKB Journal Management System, 2022; 89(2): 6831-6838. doi: 10.21608/ejhm.2022.270820

Validity of Modified Vienna-CATS Score for Prediction of Venous Thromboembolism in Egyptian Cancer Cases

The Egyptian Journal of Hospital Medicine
Article 113, Volume 89, Issue 2, October 2022, Page 6831-6838  XML PDF (597.63 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2022.270820
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Authors
Hanaa Ali El-sayed email ; Mohamed Awad Ebrahim; Hayam Rashad Ghoneim; Mohammed Ahmed Mohammed Abdallah Elagdar; Tarek El-sayed Selim
Clinical pathology, Faculty of medicine, Mansoura university
Abstract
Background: Modern oncology has a compelling problem in predicting the hazards of venous thromboembolism (VTE) linked with chemotherapy. Although thromboprophylaxis is not now advised for primary prevention, it is typically advised that cases' risks of VTE be evaluated before treatment. Great interest was given to establishing effective predictive methods for VTE in cancer cases.
The aim of this study: The study aimed to detect whether Egyptian cancer cases' VTE risk could be predicted using the modified Vienna Cancer and Thrombosis Study (CATS) score. Methods: 214 newly diagnosed cancer cases participated in a prospective cohort study completed before receiving chemotherapy. Cases who received chemotherapy were monitored for VTE episodes for six months. The Khorana score was determined. D dimer and soluble P-selectin (sP-selectin) levels were assessed, followed by a modified Vienna CATS score. For each example, the Vienna CATS score was determined. Results: Only 24 (11.2%) of the 214 cases who had follow-up experienced VTE episodes, and 5 of these (2.3%) were lost.  Conclusion: When compared to the Khorana score, the modified Vienna CATS score was more sensitive in identifying cancer cases at risk for VTE. Implementation of modified Vienna CATS in the clinical workup of cancer cases could help physicians to tailor antithrombotic therapy and lead to the perfect use of thromboprophylaxis.
 
 
Keywords
Cancer; Egypt; Vienna CATS. Abbreviations: venous thromboembolism (VTE); Cancer and Thrombosis Study (CATS); soluble P-selectin (sP-selectin)
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