Hand Strength in Rheumatoid Arthritis patients: its correlation with clinical and radiological variables
Abdelazeem, M., Salama, A., Tantawy, M. (2022). Hand Strength in Rheumatoid Arthritis patients: its correlation with clinical and radiological variables. EKB Journal Management System, 3(4), 169-182. doi: 10.21608/ejmr.2022.271019
Mervat Ismail Abdelazeem; Asmaa Salama; Marwa Tantawy. "Hand Strength in Rheumatoid Arthritis patients: its correlation with clinical and radiological variables". EKB Journal Management System, 3, 4, 2022, 169-182. doi: 10.21608/ejmr.2022.271019
Abdelazeem, M., Salama, A., Tantawy, M. (2022). 'Hand Strength in Rheumatoid Arthritis patients: its correlation with clinical and radiological variables', EKB Journal Management System, 3(4), pp. 169-182. doi: 10.21608/ejmr.2022.271019
Abdelazeem, M., Salama, A., Tantawy, M. Hand Strength in Rheumatoid Arthritis patients: its correlation with clinical and radiological variables. EKB Journal Management System, 2022; 3(4): 169-182. doi: 10.21608/ejmr.2022.271019

Hand Strength in Rheumatoid Arthritis patients: its correlation with clinical and radiological variables

Egyptian Journal of Medical Research
Volume 3, Issue 4, October 2022, Page 169-182  XML PDF (443.32 K)
Document Type: Original Article
DOI: 10.21608/ejmr.2022.271019
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Authors
Mervat Ismail Abdelazeem1; Asmaa Salama2; Marwa Tantawyorcid 1
1Rheumatology Department, Beni Suef University, Beni Suef, Egypt
2Rheumatology Department, General Hospital, Beni Suef, Egypt
Abstract
Background: In about 80-90 percent of people with rheumatoid arthritis (RA), the hands are affected. causing discomfort, stiffness, deformity, limited range of motion, and muscular weakening that have a significant impact on physical functioning and activities of daily living. The purpose of this study was to assess hand strength in patients with rheumatoid arthritis and see how it correlated with clinical and radiological characteristics.  The participants in this study were 50 RA patients as defined by the criteria of ACR/EULAR 2010, another 50 seemingly healthy participants of similar age and sex were used. Hand Strength was assessed using with Jual hand dynamometer and radiological evaluation by Plain hand and wrist radiography were taken (P-A) and lateral.   Hand Strength   measured with a hand dynamometer was substantially greater in healthy controls. Health assessment questionnaire, score ranged from (0.05) to (4.50) with an average of (1.06 ±0.58). disability of the shoulder, arm and hand score ranged from (5.80) to (85.80) with an average score of (49.25 ±19.28). Cochin Hand Function Scale score among studied RA patients ranged from (0) to (79) with an average of (34.38 ±19.28). Mean HS in right hands were (13.98 vs. 36.34), in left hands were (12.90 vs. 38.22) in RA patients. HS was significantly higher among studied RA patients with no Loco-motor manifestations as compared with RA patients with Loco-motor manifestations in both right and left hands; (p-values= 0.021 & 0.047) in right and left hands respectively.
Keywords
Rheumatoid Arthritis; Hand strength; anti-CCP antibodies; DASH score
References
  1. Akl N.Es.Es., El-Halim SMA, Mabrouk, MM, Askar DS and Hablas SA:  Role of interleukin-35 in rheumatoid arthritis pathogenesis and its relation to disease activity and joint damage. Egypt Rheumatol Rehabil 2019; 46, 177–182. https://doi.org/10.4103/err.err_37_18
  2. Safar AH, Zaki MG, Al-Zifzaf DS, El-Hilaly RA and Abaza N: Value of musculoskeletal ultrasound in assessment of rheumatoid hand function. Egyptian Journal of Radiology and Nuclear Medicine 2020; 51:207 https://doi.org/10.1186/s43055-020-00327-7
  3. Gamal RM , Mahran SA, , El Fetoh N A, Janbi F: Quality of life assessment in Egyptian rheumatoid arthritis patients: Relation to clinical features and disease activity. Egyptian rheumatologist 2016; 38: 70-65
  4. Toyoshima Y, Yajima N, Nemoto, T,   Namiki O and    Inagaki K  :  Relationship between disease activity level and physical activity in rheumatoid arthritis using a triaxial accelerometer and self-reported questionnaire. BMC Res Notes 2012; 14: 242 https://doi.org/10.1186/s13104-021-05666-w
  5. So¨derlin MK, Kautiainen H, Skogh T, Leirisalo-Repo M : Quality of life and economic burden of illness in very early arthritis. A population based study in southern Sweden. J Rheumatol 2004;31:1717–22.
  6. Bala SV, Andersson MLE, Forslind K,   Svensson B and    Hafström  I : Reported disability in relation to observed activity limitation, grip strength and physical function in women and men with rheumatoid arthritis. BMC Rheumatol .2021;5, 13  https://doi.org/10.1186/s41927-021-00184-5
  7. Larsen A : How to apply Larsen score in evaluating radiographs of rheumatoid arthritis in long-term studies J.Rheumatol 1995;22(10):1974-5.
  8. Lee KE, Choi SE, Xu H, Kang JH, Park DJ, Lee SS: HAQ score is an independent predictor of sustained remission in patients with rheumatoid arthritis. Rheumatol Int. 2017;37:2027–34.
  9. Chiari A, Sardim CC, Natour J: Translation, cultural adaptation And reproducibility of the Cochin hand functional scal questionnaire for Brazil. Clinics (Sao Paulo). 2011;66(5):731–611. DOI:10.1590/S1807-59322011000500004
  10. Aktekin LA, Eser F, Başkan BM, Sivas F, Malhan S, Öksüz E, et al: Disability of arm shoulder and hand questionnaire in Rheumatoid arthritis patients: relationship with disease activity  HAQ,SF-36. Rheumatol Int.2011;  31(6):823–6.
  11. Espinoza F, Le Blay P, Coulon D, Lieu S, Munro J, Jorgensen C, et al : Handgrip strength measured by a dynamometer connected to a smartphone: a new applied health technology solution for the self-assessment of rheumatoid arthritis disease activity. Rheumatology 2016; 55(5):897–901.
  12. Aletaha D, Neogi T,   Silman AJ,  Funovits J,  Felson DT,   Bingham CO,     Birnbaum NS et al. : 2010 Rheumatoid Arthritis Classification Criteria: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative. ARTHRITIS & RHEUMATISM 2010; 62(9): 2569–2581. DOI 10.1002/art.27584 .
  13. Wells G, Becker JC, Teng J, Dougados M, Schiff M, Smolen J, et al. Validation of the 28-joint disease activity score (DAS 28) and European league against rheumatism response criteria based on C-reactive protein against disease progression in patients with rheumatoid arthritis, and comparison with the DAS28 based on erythrocyte sedimentation rate. Ann Rheum Dis. 2009:68(6):954-60. doi:10.1136/ard.2007.084459
  14. Chiari A, Carla, Souza Sardim C, Natour J: Translation, cultural adaptation and reproducibility of the Cochin Hand Functional Scale questionnaire for Brazil. CLINICS 2011;66(5):731-736.  DOI:10.1590/S1807-59322011000500004
  15. Helen C, Roberts, Hayley J. Denison, Helen J.Martin , Harnish P .Patel, Holly syddall, Cyrus Cooper and Avan Aihie Sayer : A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach. Age Ageing 2011; 40(4):423-429.
  16. Knapp RG, Miller MC. Clinical epidemiology and biostatistics. Published by Williams &​ Wilkins; Malvern, Pa.: Harwal Pub. Co., C.
  17. Fadaa SH, Abd Elazeem MI, Mohammed RA, Sayed Tantawy M: Correlation between serum interleukins 23 and disease activity in rheumatoid arthritis. Egyptian Rheumatology and Rehabilitation 2017; 44:119-124.
  18. ten Klooster PM, Versteeg LGA, Oude Voshaar MAH,      de la Torre I,    De Leonardis F,    Fakhouri W,     Zaremba-Pechmann  L and   van de Laar M   : Radiographic progression can still occur in individual patients with low or moderate disease activity in the current treat-to-target paradigm: real-world data from the Dutch Rheumatoid Arthritis Monitoring (DREAM) registry. Arthritis Res 2019; 21:  237. https://doi.org/10.1186/s13075-019-2030-8
  19. Birtane M, Kabayel DD, Uzunca K, Unlu E, Tastekin N : The relation of hand functions with radiological damage and disease activity in rheumatoid arthritis. Rheumatol Int.2008; 28(5):407—12.
  20. BİRCAN C, ERDİNÇ GÜNDÜZ N, TEKGÜL A,  ÇETİN P, ÖNEN F, KIZIL R, GÜLBAHAR S:  Grip Ability Test in Rheumatoid Arthritis Patients: Relationship With Disease Activity and Hand-Specific Self-Report Questionnaires. RHEUMATOLOGY .2014;29(3):160-166
  21. Erol AM, Ceceli E, Uysal Ramadan S and Borman P: Effect of rheumatoid arthritis on strength, dexterity, coordination and functional status of the hand: relationship with magnetic resonance imaging findings .ACTA REUMATOL PORT 2016;41:328-337.
  22. Žura  N,  Vukorepa  M,   Jurak I,  Perić P,  Botonjić J,  Matijević A,  Mitrović H,  Laktašić Žerjavić N,  Kovač Durmiš K,   Kalebota N,  Žagar Decrease in handgrip strength in rheumatoid arthritis (RA): is there a sex-related difference?. Rheumatol Int 2021;41(10):1795-1802.  doi: 10.1007/s00296-021-04959-4. 
  23. Vallbracht I, Rieber J, Oppermann M, Förger F, Siebert Um: Diagnostic and clinical value of anti-cyclic citrullinated peptide antibodies compared with rheumatoid factor isotypes in rheumatoid arthritis. Annals of the Rheumatic Diseases 2004; 63:1079- 84
  24. Durmus E, Paker N, Bugdayci D, Goksenoglu G: Determinants of the hand functions in patients with rheumatoid arthritis Ann Med Res 2019; 26(8):1493-7. doi: 5455/annalsmedres 04.227.
  25. Quinn MA, Gough AK, Green MJ,   Devlin J,  Hensor EMA,  Greenstein A, AFraser A,  Emery P: Anti-CCP antibodies measured at disease onset help identify seronegative rheumatoid arthritis and predict radiological and functional outcome. Rheumatology (Oxford) 2006; 45:478-80. 22.
  26. Adams J, Burridge J, Mullee M, Hammond A, Cooper C:  Correlation between upper limb functional ability and structural hand impairment in an early rheumatoid population. Clin Rehabil 2004; 18:405-13.
  27. Palamar D, Terlemez R, Ustun I, Can G, Saridogan M: Disease activity, handgrip strengths, and hand dexterity in patients with rheumatoid arthritis. Clin Rheumatol 2017; 36: 2201-2208.
  28. Sferra da Silva G, Lourenço MA and Renato de Assis M: Hand strength in patients with RA correlates strongly with function but not with activity of disease. Advances in Rheumatology 2018; 58:20. https://doi.org/10.1186/s42358-018-0020-1].
  29. Poole J: Measures of Adult Hand Function. Arthritis & Rheumatism (Arthritis Care & Research) .2003; 49: 59-66.
  30. Tsai C, Lin C, Lin H, Liu M, Chiu H, Hsu H et al: How kinematic disturbance in the deformed rheumatoid thumb impacts on hand function: a biomechanical and functional perspective. Disabil Rehabil 2017; 39:338-345.
  31. Dedeoğlu M, Gafuroğlu Ŭ, Yilmaz Ö, Bodur H: The relationship between hand grip and pinch strengths and disease activity, articular damage, pain and disability in patients with rheumatoid arthritis. Turk J Rheumatol.2013; 28(2):69–77
  32. Kuper, H. H., Van Leeuwen, M. A., VanRiel, PLCM., Prevoo, MLL., Houtman, PM., Lolkema, WF., & Van Rijswijk, M. H: Radiographic damage in large joints in early rheumatoid arthritis: Relationship with radiographic damage in hands and feet, disease activity, and physical disability. British Journal of Rheumatology 1997; 36(8), 855-860. https://doi.org/10.1093/rheumatology/36.8.855
 

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