EVALUATION OF BIOLOGICAL ACTIVITIES OF MATRICARIA PUBESCENS FROM ALGERIA | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Volume 45, Issue 2, December 2022, Page 723-736 PDF (869.23 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.2022.271595 | ||||
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Authors | ||||
Mohamed taher Benmoussa 1; Said Nadji2; Soumaya Boudjemaa3; Abdelhakim Bounab4; Youcef Hadef5 | ||||
1Department of pharmacy, University of Batna2 | ||||
2Laboratory of Toxicology, University hospital of Batna, | ||||
3Laboratory of Toxicology, University hospital of Batna | ||||
4Laboratory of mineral chemistry, Faculty of pharmacy, University of Algiers | ||||
5Laboratory of Analytical chemistry, Department of pharmacy, Faculty of Medicine, University of Annaba | ||||
Abstract | ||||
Abstract: Matricaria pubescens is a plant of the asteraceae family that grows wild in Algeria and throughout North Africa especially in the desert. It is commonly used as folk medicine to cure a variety of ailments in various preparations, aerial parts of the plant were sampled from two different sites in Algeria, the biological activities of the methanolic extracts and essential oils have been evaluated namely antioxidant, anti-inflammatory, antidiabetic, antibacterial, and antifungal activities, besides a safety bioassay , The essential oils of the plant have shown significant efficacy against the studied bacteria, and a strong antifungal activity against Candida albicans. Methanolic extracts and essential oils have shown noticeable anti-inflammatory activity. The essential oils showed good antidiabetic activity and weak antioxidant power. Meanwhile Matricaria pubecens essential oils noted significant cytolytic effect that may hamper its systemic use, it also noteworthy to mention the variability between the samples confirming the differences in the chemical patterns. | ||||
Keywords | ||||
Essential oil; Methanolic extracts; Biological activities; Matricaria pubescens; toxicity | ||||
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