Authentication of Cherry (Muntingia calabura) Fruit from different Geographical Locations in Indonesia by FTIR Spectroscopy Combined with Chemometrics and Their Antioxidant and Antiaging Activities | ||||
Egyptian Journal of Chemistry | ||||
Volume 66, Issue 13, December 2023, Page 2379-2388 PDF (714.51 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejchem.2022.168226.7079 | ||||
View on SCiNiTO | ||||
Authors | ||||
Syamsu Nur 1; Andi Nur Aisyah 2; Asril Burhan 3; Fitriyanti Jumaetri Sami 1; Nursamsiar Nursamsiar 1; Amriani Sapra 2; Megawati Megawati 1 | ||||
1Department of Pharmaceutical Chemistry, Sekolah Tinggi Ilmu Farmasi Makassar | ||||
2Department of Pharmaceutical Technology, Sekolah Tinggi Ilmu Farmasi Makassar | ||||
3Sekolah tinggi ilmu farmasi makassar | ||||
Abstract | ||||
Cherry (Muntingia calabura L) is a plant with scientific properties in various treatments. Cherry can overgrow in a variety of environments. This study aims to determine the similarity profile of the compound content of cherries obtained at different geographical locations using the FT-IR-chemometric spectroscopy approach and their bioactivity as antioxidants and anti-aging. Cherry fruit obtained from 8 regions in South Sulawesi Province-Indonesia was dried and extracted using the sonicator method for 30 minutes. The extract obtained was analyzed by FT-IR spectroscopy and authenticated by the chemometric similarity of the compounds (PCA and Cluster analysis). The test results showed that the ethanol extract of cherry fruit from various regions had a similarity of 65.4% and, by dendogram, tended to form 2 clusters based on the profile of chemical content and intensity. Antioxidant activity profiles using DPPH and ABTS methods showed that bioactivity varied from strong to powerful. The same thing was also found in the anti-elastase activity showing variations based on a percentage of elastase inhibition and the IC50 value. But overall, the various test results did not significantly affect the bioactivity of cherry fruit as an antioxidant and anti-aging. | ||||
Keywords | ||||
Authentication; Antioxidant; Anti-aging; Chemometric; Elastase, FT-IR Profile, Muntingia calabura | ||||
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