Synthesis, Characterization, Antimicrobial/Antitumor Activity of Binary and Ternary Neodymium (III) Complex with 2,2'-((1E,1'E)-(ethane-1,2-diylbis(azaneylylidene)) bis(methaneylylidene)) diphenol and Imidazole
Abdalla, E., Abd-Allah, M. (2022). Synthesis, Characterization, Antimicrobial/Antitumor Activity of Binary and Ternary Neodymium (III) Complex with 2,2'-((1E,1'E)-(ethane-1,2-diylbis(azaneylylidene)) bis(methaneylylidene)) diphenol and Imidazole. EKB Journal Management System, 65(131), 735-744. doi: 10.21608/ejchem.2022.179421.7282
Ehab M. Abdalla; M. T. Abd-Allah. "Synthesis, Characterization, Antimicrobial/Antitumor Activity of Binary and Ternary Neodymium (III) Complex with 2,2'-((1E,1'E)-(ethane-1,2-diylbis(azaneylylidene)) bis(methaneylylidene)) diphenol and Imidazole". EKB Journal Management System, 65, 131, 2022, 735-744. doi: 10.21608/ejchem.2022.179421.7282
Abdalla, E., Abd-Allah, M. (2022). 'Synthesis, Characterization, Antimicrobial/Antitumor Activity of Binary and Ternary Neodymium (III) Complex with 2,2'-((1E,1'E)-(ethane-1,2-diylbis(azaneylylidene)) bis(methaneylylidene)) diphenol and Imidazole', EKB Journal Management System, 65(131), pp. 735-744. doi: 10.21608/ejchem.2022.179421.7282
Abdalla, E., Abd-Allah, M. Synthesis, Characterization, Antimicrobial/Antitumor Activity of Binary and Ternary Neodymium (III) Complex with 2,2'-((1E,1'E)-(ethane-1,2-diylbis(azaneylylidene)) bis(methaneylylidene)) diphenol and Imidazole. EKB Journal Management System, 2022; 65(131): 735-744. doi: 10.21608/ejchem.2022.179421.7282

Synthesis, Characterization, Antimicrobial/Antitumor Activity of Binary and Ternary Neodymium (III) Complex with 2,2'-((1E,1'E)-(ethane-1,2-diylbis(azaneylylidene)) bis(methaneylylidene)) diphenol and Imidazole

Egyptian Journal of Chemistry
Volume 65, Issue 131, December 2022, Page 735-744  XML PDF (716.01 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2022.179421.7282
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Authors
Ehab M. Abdalla email orcid 1; M. T. Abd-Allah2
1Chemistry Department, Faculty of Science, New Valley University, Alkharga 72511, Egypt
2Ministry of higher education, Technical Industrial Institutes, Sohag, Egypt
Abstract
Two new Neodymium(III) complexes with ligand, 2,2'-((1E,1'E)-(ethane-1,2-diylbis(azaneylylidene)) bis(methaneylylidene)) diphenol (H2L) [Nd(H2L)2Cl2]Cl.H2O, and H2L mixed with imidazole (I) [Nd(H2L)2(I)]Cl3.H2O were prepared and characterized with physicochemical methods were used to clarify the structural makeup of the new compounds. [Nd(H2L)Cl2]Cl.H2O and [Nd(H2L)(I)Cl2]H2O were effective antimicrobials, with larger inhibition zones than the reference antibiotic. The antimicrobial efficacy follows the order: gentamicin > [Nd(H2L)(I)Cl2]H2O > [Nd(H2L)Cl2]Cl.H2O > H2L/I > H2L. The cytotoxicity of ligand, binary and ternary complexes against human liver (Hep-G2) and breast (MDA-MB231) carcinoma cell lines was determined by using cisplatin as reference, the complex of [Nd(H2L)(I)Cl2]H2O exhibited the highest activity against two cell lines
Keywords
Complex; Imidazole; Neodymium; Antimicrobial; Cytotoxicity
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