TRIALS FOR PREPARATION OF INACTIVATED BIVALENT AVIAN ENCEPHALOMYELITIS AND REO VIRUS VACCINE | ||||
Egyptian Journal of Agricultural Research | ||||
Article 30, Volume 82, Issue 3, September 2004, Page 1439-1453 PDF (3.28 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejar.2004.274856 | ||||
View on SCiNiTO | ||||
Authors | ||||
HALA M. EL-MAKAKY; MOHAMED A. ABOUL EL-KHAIR; MERVAT A. EL-KOFFY; MOHAMED S. MADKOUR; NADIA M. IBRAHIM; FEKRIA AL. BORDINY | ||||
Veterinary Serum and Vaccine Research Institute, Agricultural Research Center, Ministry of Agriculture, Dokki, Giza, Egypt | ||||
Abstract | ||||
Inactivated monovalent and bivalent oil adjuvanted vaccines against Avian Encephalomyelitis (AE) and Reo viruses were prepared. Immunological responses to such experimental vaccines were evaluated by injecting them into groups of susceptible thickens. Blood samples were collected at weekly intervals. Serological and cellular immune response were evaluated by SNT, lymphocyte blastogenesis and macrophage activity test, respectively. The vaccinated chicks were subjected to challenge tests against both viruses. The results indicated that prepared vaccine was effident, safe, immunogenic and produced satisfactory dual protection against AE and Reo viruses infection. | ||||
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