Microspheres as a platform for drug delivery | ||||
| Delta University Scientific Journal | ||||
| Volume 5, Issue 2, September 2022, Page 122-126 PDF (260.53 K) | ||||
| Document Type: Original research papers | ||||
| DOI: 10.21608/dusj.2022.275427 | ||||
 View on SCiNiTO | ||||
| Author | ||||
| Heba Elagamy | ||||
| Abstract | ||||
| Microspheres are promising drug delivery system with a particle size ranging from 1- 1000 micrometer. Microspheres have relatively small particle size and efficient drug loading capacity. They have many advantages as a drug carrier especially extended drug effect and selective targeting of anticancer drugs for tumor cells. Microspheres have different types and can be formulated via several techniques allowing variety in their application as a drug delivery platform. Microspheres can be loaded with different types of drugs, they are biocompatible and can be prepared from biodegradable particles. Microspheres have been implemented for different routes of administration including buccal, oral, ocular and transdermal showing enhanced therapeutic effects. This review aims to highlight the advantages of microspheres, types of microspheres including (bioadhesive, floating, magnetic, radioactive and polymeric), different methods of preparation including (Single emulsion technique, Double emulsion method, Coacervation method, Spray drying technique, Polymerization techniques and Freeze Drying) and their pharmaceutical applications. | ||||
| Keywords | ||||
| polymers; bioadhesive; floating; spray drying | ||||
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