VITAMIN D LEVEL IN RHEUMATOID ARTHRITIS PATIENTS IN SAUDI ARABIA AND ITS CORRELATION WITH DISEASE ACTIVITY AND MOOD CHANGES
Abdelnaser, N., Abdul Basset, S., Elkhouly, R., Mahdy, H., Ibrahim, A. (2023). VITAMIN D LEVEL IN RHEUMATOID ARTHRITIS PATIENTS IN SAUDI ARABIA AND ITS CORRELATION WITH DISEASE ACTIVITY AND MOOD CHANGES. EKB Journal Management System, 40(2), 317-332. doi: 10.21608/bmfj.2022.174640.1707
Noha Maher Abdelnaser; Shaza Abdul Basset Abdul Basset; Rasha Mohamed Soubhy Elkhouly; Hanan Abdelaziz Mahdy; Ahmed Abdelaziz Ibrahim. "VITAMIN D LEVEL IN RHEUMATOID ARTHRITIS PATIENTS IN SAUDI ARABIA AND ITS CORRELATION WITH DISEASE ACTIVITY AND MOOD CHANGES". EKB Journal Management System, 40, 2, 2023, 317-332. doi: 10.21608/bmfj.2022.174640.1707
Abdelnaser, N., Abdul Basset, S., Elkhouly, R., Mahdy, H., Ibrahim, A. (2023). 'VITAMIN D LEVEL IN RHEUMATOID ARTHRITIS PATIENTS IN SAUDI ARABIA AND ITS CORRELATION WITH DISEASE ACTIVITY AND MOOD CHANGES', EKB Journal Management System, 40(2), pp. 317-332. doi: 10.21608/bmfj.2022.174640.1707
Abdelnaser, N., Abdul Basset, S., Elkhouly, R., Mahdy, H., Ibrahim, A. VITAMIN D LEVEL IN RHEUMATOID ARTHRITIS PATIENTS IN SAUDI ARABIA AND ITS CORRELATION WITH DISEASE ACTIVITY AND MOOD CHANGES. EKB Journal Management System, 2023; 40(2): 317-332. doi: 10.21608/bmfj.2022.174640.1707

VITAMIN D LEVEL IN RHEUMATOID ARTHRITIS PATIENTS IN SAUDI ARABIA AND ITS CORRELATION WITH DISEASE ACTIVITY AND MOOD CHANGES

Benha Medical Journal
Article 1, Volume 40, Issue 2, September and October 2023, Page 317-332  XML PDF (857.89 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2022.174640.1707
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Authors
Noha Maher Abdelnaser email 1; Shaza Abdul Basset Abdul Bassetorcid 2; Rasha Mohamed Soubhy Elkhouly3; Hanan Abdelaziz Mahdy4; Ahmed Abdelaziz Ibrahim2
1Department of rheumatology, physical medicine and rehabilitation, Benha Faculty of Medicine, Benha University,Benha , Egypt
2Department of rheumatology, rehabilitation and physical medicine, Benha Faculty of Medicine, Benha University, Benha, Egypt.
3Department of psychiatry, Kuwait Center for Mental Health (KCMH), Ministry of Health, Kuwait City, Kuwait.
4Department of internal medicine, Ain Shams Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Abstract
Background: Patients with rheumatoid arthritis (RA) are more susceptible for having psychological comorbidities than the normal population. This is due to many factors like pain, disability, and social impacts of the arthritis besides other metabolic co-factors like vitamin D deficiency. Purpose: To study the link between vitamin D level as a co-factor in mood changes outcome in RA patients and the extent of mood change variables affection as well as the relation to disease activity. Patients and Methods: This study included 100 adult RA patients divided into two groups; Group1(G1): RA patients with low vitamin D level and Group 2(G2):RA patients with normal vitamin level, both groups were subjected to assessment of mood change and disease activity. Results: This study found that total Beck scale for depression and mood change variables were significantly different between the two groups (p < 0.001). Significant correlation was also found between vitamin D level and total Beck scale and mood changes (P,0.001). Disease activity index was in reverse correlation with vitamin D level in total patients’ sample (r = - 0.143), but no significant difference was found between both groups (p = 0.139). Conclusion: Patients with rheumatoid arthritis who have vitamin D deficiencies are more prone to exhibit psychological and mood disorders regardless the status of disease activity.
Keywords
Rheumatoid Arthritis; Vitamin D; Mood Changes; Rheumatoid Arthritis Disease Activity Score; Beck Scale
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