IMMUNE RESPONSE OF SHEEP VACCINATED WITH INACTIVATED COMBINED FOOT AND MOUTH DISEASE, RIFT VALLEY FEVER AND SHEEP PDX VACCINE | ||||
Egyptian Journal of Agricultural Research | ||||
Article 31, Volume 82, Issue 4, December 2004, Page 1893-1904 PDF (2.9 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejar.2004.275798 | ||||
View on SCiNiTO | ||||
Authors | ||||
ABEER A. TALAAT; MERVATE M. ALI; LILY S. SALAMA | ||||
Veterinary Serum and Vaccine Research Institute, Agricultural Research Center, Ministry of Agriculture, Dokki, Giza, Egypt | ||||
Abstract | ||||
A combined vaccine was constructed to contain FMD 01, RVF ZH5,01 and sheep pox Egyptian strain inactivated with Binary ethylenemine (BEI) and adsorbed on aluminium hydroxide gel. Comparative studies were conducted to evaluate the prepared vaccines (three monovalent FMD, RVF and Sheep Pox separately and the combined one). It was found that the serum neutralization antibody titer of sheep vaccinated with the combined vaccine (FMD and RVF) reached its peak earlier than those vaccinated with each as monovalent vaccine, separately, while, there was no significant difference in efficacy of immune response between combined vaccine and sheep pox vaccine. So, it is recommended that animals should be boostered at the 4th week post the first dose. | ||||
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