EVALUATION OF FOWL CHOLERA VACCINE BY MICE VACCINATION AND CHALLENGE INOCULATION SYSTEM | ||||
Egyptian Journal of Agricultural Research | ||||
Article 23, Volume 81, Issue 1, March 2003, Page 311-322 PDF (2.56 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejar.2003.276332 | ||||
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Authors | ||||
SAMY M. SHAFEI1; ELHAM A. EL-EBIARY1; SAFWAT K. ROFAIIL2; SAHER M. GERGIS2 | ||||
1Central Laboratory for Control of Veterinary Biologics, Agricultural Research Centre, Dokki, Giza, Egypt | ||||
2Veterinary Serum and Vaccine Research Institute, Agricultural Research Centre, Dokki, Giza, Egypt | ||||
Abstract | ||||
In the present study, S lots of commercial fowl cholera vaccines were evaluated by different methods. Results indicated that the lots failed to pass the two stages protection test in chicken. Comparable results were obtained by conducting either active immunization in mice or by the mouse vaccination challenge inoculation system. From the obtained results it can be concluded that mice can be used instead of chickens for evaluating fowl cholera vaccines as they are more cheaper and less susceptible to viral diseases that may complicate the evaluation test procedure in chicken. | ||||
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