Impact Of RV Lead Positioning On Global Longitudinal Strain As A Surrogate Of Clinical Response In Patients With Non-Ischemic Cardiomyopathy Treated By Cardiac Resynchronization Therapy
Abdelmonaem, M., Nour, A., Kadry, A., Reda, A. (2022). Impact Of RV Lead Positioning On Global Longitudinal Strain As A Surrogate Of Clinical Response In Patients With Non-Ischemic Cardiomyopathy Treated By Cardiac Resynchronization Therapy. EKB Journal Management System, 89(2), 7542-7548. doi: 10.21608/ejhm.2022.276681
Mostafa Abdelmonaem; Amira Nour; Ahmed Kadry; Ahmed Reda. "Impact Of RV Lead Positioning On Global Longitudinal Strain As A Surrogate Of Clinical Response In Patients With Non-Ischemic Cardiomyopathy Treated By Cardiac Resynchronization Therapy". EKB Journal Management System, 89, 2, 2022, 7542-7548. doi: 10.21608/ejhm.2022.276681
Abdelmonaem, M., Nour, A., Kadry, A., Reda, A. (2022). 'Impact Of RV Lead Positioning On Global Longitudinal Strain As A Surrogate Of Clinical Response In Patients With Non-Ischemic Cardiomyopathy Treated By Cardiac Resynchronization Therapy', EKB Journal Management System, 89(2), pp. 7542-7548. doi: 10.21608/ejhm.2022.276681
Abdelmonaem, M., Nour, A., Kadry, A., Reda, A. Impact Of RV Lead Positioning On Global Longitudinal Strain As A Surrogate Of Clinical Response In Patients With Non-Ischemic Cardiomyopathy Treated By Cardiac Resynchronization Therapy. EKB Journal Management System, 2022; 89(2): 7542-7548. doi: 10.21608/ejhm.2022.276681

Impact Of RV Lead Positioning On Global Longitudinal Strain As A Surrogate Of Clinical Response In Patients With Non-Ischemic Cardiomyopathy Treated By Cardiac Resynchronization Therapy

The Egyptian Journal of Hospital Medicine
Article 214, Volume 89, Issue 2, October 2022, Page 7542-7548  XML PDF (542.42 K)
DOI: 10.21608/ejhm.2022.276681
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Authors
Mostafa Abdelmonaem* ; Amira Nour; Ahmed Kadry; Ahmed Reda
Department of Cardiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Abstract
Background:  Cardiac resynchronization therapy (CRT) provides an excellent therapeutic option for patients with heart failure and reduced systolic functions, optimizing the CRT implantation procedure is mandatory to improve clinical response. The site of right ventricle (RV) pacing remains a puzzling issue that needs to be solved to assess the impact of non-apical RV pacing on CRT clinical and echocardiographic response.
Objective:  To compare the impact of RV apical pacing versus RV septal pacing in patients with non-ischemic cardiomyopathy treated by CRT in terms of global longitudinal stain, 6 minutes walk test, and QRS complex width.
Patients and Methods: An observational prospective trial study was conducted on 100 patients with dilated cardiomyopathy who were candidates for CRT implantation. Fifty consecutive patients had RV pacing lead in the apical position and the other 50 consecutive patients had the pacing lead in mid septal position.
Results: The GLS significantly increased post-procedure within the whole patients (11.9 ±2 vs. 11 ±2.1), the apical group (12.1 ±1.9 vs. 11.1 ±2.1), and the septal group (11.8 ±2.1 vs. 10.9 ±2.1) (P < 0.001 for each). No significant difference was detected between both groups of patients regarding QRS width, 6 min walking test, and GLS. A positive correlation was found between delta GLS and % of 6 minutes walk test among the group of patients with mid-septal RV lead position.
Conclusion: This study concluded that septal RV pacing is not superior to standard RV apical pacing in patients with non-ischemic cardiomyopathy candidate for CRT, in terms of clinical and echocardiographic response
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