Bisphenol A in Children with Bronchial Asthma and Its Relation to Body Mass Index | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 263, Volume 89, Issue 2, October 2022, Page 7856-7864 PDF (671 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2022.277376 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Hend M. Soliman; Doaa Mohammed Abdou Mostafa; Dina A ezzat   ; Dina Abdullah; Mona Mohsen
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| clinical pathology depart faculty of medicine kasralainy cairo university | ||||
| Abstract | ||||
| Background: One of the most debilitating diseases in children is bronchial asthma. Little research has been conducted into the relationship between bisphenol A (BPA), a commonly recycled monomer, which is linked to childhood obesity and asthma. Objective: This study's aimed to examine the relationships between paediatric obesity morbidity and bisphenol A (BPA). Subjects and Methods:100 kids between 4 and 10 years were included in this study (25 asthmatics, 25 asthmatics with obesity, 25 obese non-asthmatics, and 25 healthy controls). The diagnosis of asthmatic children was made according to GINA guidelines (Global Initiative for Asthma). The BPA competitive ELISA Kit was used to measure the BPA levels in urine specimens. Looked up for the effect of BPA as a predictor of asthma development in asthmatic children. Additionally, research was done on BPA's potential role in the prediction of childhood obesity. Results: High median total urinary BPA levels (p > 0.001) detected significantly in children with asthma and obesity. Increased levels of BPA were found to be a significant predictor (p = 0.006) in an analysis using multiple logistic regression of asthma predictors. Conclusions: It's possible that BPA played a role in the development of bronchial asthma & obesity, based on the correlation between high BPA levels in urine with asthma diagnostic assessments and children obesity. There is a need for more clinical and biochemical study. | ||||
| Keywords | ||||
| Asthma; Bisphenol A; Obesity; ELISA | ||||
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