Linear Growth of Children with Congenital Adrenal Hyperplasia | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 270, Volume 89, Issue 2, October 2022, Page 7906-7910 PDF (568.92 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2022.277388 | ||||
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| Authors | ||||
Hanaa Abdel-Lateef Mohammad; Faisal-AlKhateeb Ahmad; Ali Hussin Mohamed Hussin 
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| Abstract | ||||
| Background: Helping children with congenital adrenal hyperplasia (CAH) to reach a normal adult final height is the main goal of treatment. Objective: The aim of the current study is to evaluate the linear growth in kids and teens with congenital adrenal hyperplasia. Patients and methods: A cross sectional study was conducted on 71 Egyptian children with CAH who attended the Diabetes and Endocrine Pediatric Unit at Assiut University Children Hospital, Assiut, Egypt in the period from the start of January 2020 to the end of December 2020. A control group included 71 healthy children matched for age and sex. Results: A total 71 Egyptian children with CAH were recruited; 28 females and 43 males. Of the recruited children, 60 of them were salt loosing type and 11 of them were simple virilizing. The median age at presentation was 5 years and ranged from 1 up to 13 years old. Positive family history was documented in 13 (18.3%) patients. CAH cases were significantly stunted compared to controls (P<0.001). Those presented with salt loosing CAH have significantly lower height and significantly higher BMI as compared to their controls. Conclusions: The multifaceted issue of linear growth in children with CAH is significant. In order to restore normal adult final height in these patients, it is crucial that the condition is appropriately controlled clinically and biochemically through stringent adherence to medicinal therapy as well as continued clinical and laboratory surveillance. | ||||
| Keywords | ||||
| Linear growth; Congenital adrenal hyperplasia; Final adult height; Case control study; Assiut University | ||||
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