Systematic Review 2022: Effect of probiotics versus herbal remedies on infantile colic
Ahmad, G., Abdel Wahab, H., Elkronfoly, E., Rabie, F., Mohamed, S., Mostafa, S., Sharaf, S. (2022). Systematic Review 2022: Effect of probiotics versus herbal remedies on infantile colic. EKB Journal Management System, 60(2), 180-211. doi: 10.21608/bnni.2022.277931
Gihan F Ahmad; Hanna M Abdel Wahab; Eman I Elkronfoly; Fatma EO Rabie; Samah A Mohamed; Sara MN Mostafa; Shireen S Sharaf. "Systematic Review 2022: Effect of probiotics versus herbal remedies on infantile colic". EKB Journal Management System, 60, 2, 2022, 180-211. doi: 10.21608/bnni.2022.277931
Ahmad, G., Abdel Wahab, H., Elkronfoly, E., Rabie, F., Mohamed, S., Mostafa, S., Sharaf, S. (2022). 'Systematic Review 2022: Effect of probiotics versus herbal remedies on infantile colic', EKB Journal Management System, 60(2), pp. 180-211. doi: 10.21608/bnni.2022.277931
Ahmad, G., Abdel Wahab, H., Elkronfoly, E., Rabie, F., Mohamed, S., Mostafa, S., Sharaf, S. Systematic Review 2022: Effect of probiotics versus herbal remedies on infantile colic. EKB Journal Management System, 2022; 60(2): 180-211. doi: 10.21608/bnni.2022.277931

Systematic Review 2022: Effect of probiotics versus herbal remedies on infantile colic

Bulletin of the National Nutrition Institute of the Arab Republic of Egypt
Volume 60, Issue 2, December 2022, Page 180-211  XML PDF (602.13 K)
Document Type: Original Article
DOI: 10.21608/bnni.2022.277931
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Authors
Gihan F Ahmad1; Hanna M Abdel Wahab1; Eman I Elkronfoly* 2; Fatma EO Rabie3; Samah A Mohamed4; Sara MN Mostafa5; Shireen S Sharaf6
1National Nutrition Institute
2Qaha specialized hospital, ministry of health
3Manshyat Elbakry general hospital, ministry of health.
4Berket El-Sabae hospital, ministry of health
5Alexandria police hospital
6El-menshawy general hospital, ministry of health
Abstract
Infantile colic is one of the most distressing early-life manifestations. Sudden episodes of inconsolable crying without a clear reason or treatment plan might cause parents to try incorrect methods, which can injure the infant. Many treatment strategies were developed to solve this dilemma; the effectiveness of each is still doubtful. Objective: To compare the effect of probiotics as a recent therapy in the management of infant colic and herbal remedies as one of the most commonly used strategies. By searching national and international databases, 24 randomized clinical trials RCT studies were included (19 examining the effect of probiotics, 5 for herbal remedies). Results: The most researched probiotic, Lactobacillus reuteri, exhibits statistically significant improvement and a decrease in the daily average crying time >=50% on days 7, 14, and 21. On day 7, RR (95% CI): 4.3 (2.3-8.7), P value 0.026; on day 14, RR (95% CI): 4.3 (2.3-8.7), P value< .001. A phase III, double-blind, randomized placebo-controlled trial found that the lactobacillus reuteri group cried or fussed for 49 minutes longer than the placebo group, (95% confidence interval 8 to 90 minutes, P=0.02). Fennel emulsion was the most studied in the herbal group with significant improvement to the placebo group (p< 0.01) absolute risk reduction (ARR):41% (95% CI 25 to 57). Conclusions: None of the therapies shows dramatic improvement, and probiotic supplementation's long-term effects are still a concern. More research is needed including local herbal remedies of our community.
Keywords
(herbal for infant colic); (probiotic for infant colic)
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