Evaluation of Neutrophil to Lymphocyte Ratio in Patients with Chronic Spontaneous Urticaria | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 21, Volume 90, Issue 1, January 2023, Page 139-142 PDF (281.04 K) | ||||
| DOI: 10.21608/ejhm.2023.279216 | ||||
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| Author | ||||
Hossam Moustafa Elkady 
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| Department of Internal Medicine, Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt. | ||||
| Abstract | ||||
| Background: Chronic spontaneous urticaria (CSU) is an immune-inflammatory disorder. The urticaria activity score (UAS 7) is used to assess urticaria activity. The neutrophil to lymphocyte ratio (NLR) is a reliable indicator for inflammatory conditions. Parameters useful for the evaluation of patients with CSU are not currently available. Objectives: To assess NLR in CSU patients and its correlation with urticaria activity score. Patients and methods: Of the patients attending the allergy clinic of Ain Shams University Hospital, 200 patients with CSU, including 62 patients with mild disease, 68 with moderate disease, and 70 with severe disease according to urticaria activity score 7 (UAS7), and 200 controls, were included in this study. NLR values were compared among various study groups. Results: NLR values were significantly higher among CSU patients than controls (p < 0.001), with no significant correlation with urticaria activity score. Conclusion: NLR is a rapid, simple, and low-cost blood marker that can be used to detect systemic inflammatory processes in patients with CSU. | ||||
| Keywords | ||||
| Neutrophil to lymphocyte ratio; Chronic spontaneous urticaria; Urticaria activity score | ||||
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