Incidence and predictors of acute oesophageal variceal haemorrhage in patients with spontaneous bacterial peritonitis
Diasty, M., El-mesery, A., Taha, K., Elnaggar, M., Mousa, E., Yassen, A. (2022). Incidence and predictors of acute oesophageal variceal haemorrhage in patients with spontaneous bacterial peritonitis. EKB Journal Management System, 7.1(1), 1-7. doi: 10.21608/mjvh.2022.279330
Muhammad Diasty; Ahmed El-mesery; Khaled Taha; Mohamed Elnaggar; Eman Mousa; Ahmed Yassen. "Incidence and predictors of acute oesophageal variceal haemorrhage in patients with spontaneous bacterial peritonitis". EKB Journal Management System, 7.1, 1, 2022, 1-7. doi: 10.21608/mjvh.2022.279330
Diasty, M., El-mesery, A., Taha, K., Elnaggar, M., Mousa, E., Yassen, A. (2022). 'Incidence and predictors of acute oesophageal variceal haemorrhage in patients with spontaneous bacterial peritonitis', EKB Journal Management System, 7.1(1), pp. 1-7. doi: 10.21608/mjvh.2022.279330
Diasty, M., El-mesery, A., Taha, K., Elnaggar, M., Mousa, E., Yassen, A. Incidence and predictors of acute oesophageal variceal haemorrhage in patients with spontaneous bacterial peritonitis. EKB Journal Management System, 2022; 7.1(1): 1-7. doi: 10.21608/mjvh.2022.279330

Incidence and predictors of acute oesophageal variceal haemorrhage in patients with spontaneous bacterial peritonitis

Medical Journal of Viral Hepatitis
Article 1, Volume 7.1, Issue 1, December 2022, Page 1-7  XML PDF (245.87 K)
Document Type: Original article
DOI: 10.21608/mjvh.2022.279330
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Authors
Muhammad Diasty1; Ahmed El-mesery email 2; Khaled Taha3; Mohamed Elnaggar3; Eman Mousa4; Ahmed Yassen1
1Tropical Medicine Department, Mansoura University, Mansoura, Egypt
2Tropical Medicine Department, Mansoura University, Mansoura, Egypt.
3Internal Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt
4Faculty of Dentistry, Mansoura University, Mansoura, Egypt
Abstract
Background: Rupture oesophageal varices (REV) is a life-threatening complication of liver cirrhosis. Bacterial infection is linked with the risk of variceal bleeding through complex pathophysiologic pathways. Spontaneous bacterial peritonitis (SBP) is the commonest well-known bacterial infection in patients with cirrhosis. the aim of this study is to estimate the incidence and predictors of REV in cirrhotic patients with SBP.
Patients and methods: 389 patients with cirrhotic ascites out of 2880 patients with ascites and/or acute gastrointestinal bleeding were divided into two groups, group 1 included 189 patients with SBP and group 2 included 200 patients without SBP. Routine clinical and laboratory data were collected. Results: Compared to patients without SBP, patients with SBP had significant higher incidence of oesophageal variceal hemorrhage (25.4% in patients with SBP versus 14% in patients without SBP (P =0.004). multivariate analysis for factors associated with oesophageal variceal haemorrhage in patients with SBP demonstrated that, the independent predictors for rupture oesophageal varices in patients with SBP were, increased age (p value= 0.001) with EXP(B) 1.068; 95.0% C.I. was (1.026-1.113), presence of fever (p value= 0.005) with EXP(B) 3.433; 95.0% C.I. was (1.458-8.083) and hepatic encephalopathy (p value= 0.039) with EXP(B) 3.159; 95.0% C.I. was (1.060-9.421). Conclusion: Spontaneous bacterial peritonitis increases the risk of oesophageal variceal haemorrhage. Increased age, presence of fever and hepatic encephalopathy were independent predictors of acute oesophageal variceal haemorrhage in patients with SBP.
Keywords
Acute oesophageal variceal haemorrhage; oesophageal varices; spontaneous bacterial peritonitis; liver cirrhosis
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