Outcome of On-Demand Tadalafil in Premature Ejaculation | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 106, Volume 90, Issue 1, January 2023, Page 754-756 PDF (442.02 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2023.279926 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Mohammad Sayed Abdel-Kader; Ahmed Mahmoud Hasan; Mahmoud Mohsen Mohammed; Gamal A. Alsagheer | ||||
| Abstract | ||||
| Background: One of the most prevalent sexual diseases among men is premature ejaculation (PE). Phosphodiesterase type-5 (PDE5) inhibitors used on-demand were successful in treating PE, according to several studies. Aims: To evaluate the safety and the efficacy of tadalafil in treatment of patients with premature ejaculation. Patients and methods: This study was conducted on 30 patients with at least a 3-month history of PE. All patients were submitted to clinical examination with stress on genital examination, laboratory testing for complete blood picture, and hormonal profile. Patients were received on-demand 20 mg tadalafil 2 hours before intercourse. Intravaginal ejaculatory latency time (IELT) was measured in all patients before and after the treatment (at 4, 8, and 12 weeks). Results: The mean age was 33.03 ± 7.5 years, with mean body mass index (BMI) of 28.8 ± 2.9 kg/m². The baseline IELT score was 39.4 ± 10. There was highly statistically significant (p-value < 0.001) increased 4 weeks IELT score (186.6 ± 24.4), 8 weeks IELT score (188.5 ± 21) and 12 weeks IELT score (187.2 ± 20.5) when compared with baseline IELT score (39.4 ± 10). Conclusion: Tadalafil 20 mg on demand is thought to help PE patients with good levels of safety and tolerability. | ||||
| Keywords | ||||
| Tadalafil; Premature ejaculation; IELT score | ||||
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