A Comprehensive Review on Bisphenol A (BPA) Toxicity Updates: Controversy Is Not Over Yet | ||||
| Mansoura Journal of Forensic Medicine and Clinical Toxicology | ||||
| Volume 31, Issue 2, July 2023, Page 3-15 PDF (364.05 K) | ||||
| Document Type: Review article | ||||
| DOI: 10.21608/mjfmct.2023.177759.1058 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Aya Magdy Elkady1; Rasha Elhaddad Ali Mousa   2; Mai Mostafa Abdelkader3; Hend Gamal Aref4; Azza Omar Hassan1
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| 1Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Sohag University, Egypt. | ||||
| 2Forensic Medicine and Clinical Toxicology, faculty of Medicine, Sohag University, Sohag, Egypt | ||||
| 3Forensic Medicine and Clinical Toxicology Department-Faculty of Medicine- Sohag University, Sohag, Egypt | ||||
| 4Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Sohag University, Sohag, Egypt. | ||||
| Abstract | ||||
| Bisphenol A (BPA) is a commonly used industrial chemical in plastics production. It is present in different types of plastics as polycarbonate and epoxy resin. Plastics that contain BPA are used for various purposes as food containers, medical equipment, and toys. So, BPA exposure is almost universal among humans. Food and water have been recognized as significant BPA exposure sources. Other sources include waste smoke, thermal paper, and dental materials. Since it was created, concerns regarding BPA safety and health hazards have been raised. Research over a decade showed multiple health hazards of BPA in humans. Bisphenol A is known to be a hormonal disruptor interfering with regular hormonal activity in the body. In addition, it has a cytotoxic effect by increasing free radicals. BPA is linked to many diseases affecting the reproductive, endocrine, nervous, and immune systems and different types of cancer. The FDA and other health-related institutions have regulated the use of BPA plastics. However, a debate is unsolved as regards the safe dose of BPA for daily human exposure. This article explores the toxic aspects of BPA and discusses the different regulations relating to BPA use. | ||||
| Keywords | ||||
| Bisphenol A; BPA; human toxicity; polycarbonate; epoxy resin | ||||
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