THE ROLE OF LOCAL ESTROGEN THERAPY IN POSTMENOPAUSAL OVERACTIVE BLADDER | ||||
ALEXMED ePosters | ||||
Article 1, Volume 5, Issue 1, January 2023, Page 12-13 | ||||
Document Type: Preliminary preprint short reports of original research | ||||
DOI: 10.21608/alexpo.2023.187538.1547 | ||||
View on SCiNiTO | ||||
Authors | ||||
Wafaa Aboulenein1; Tamer Abd Aldayem2; Dina Hesham Abd El-Galil Elhedeny 3 | ||||
1Obstetrics and Gynecology Department, Faculty of Medicine, Alexandria University, Egypt | ||||
2Obstetric and Gynecology department, faculty of Medicine, Alexandria University, Alexandria | ||||
3Department of Obstetrics and Gynecology, Faculty of Medicine - Alexandria University | ||||
Abstract | ||||
Overactive bladder (OAB) is relatively common in the general population but more common in women, especially in postmenopausal women with the genitourinary syndrome of menopause (GSM). AIM OF THE WORK: The aim of this study was to assess the efficacy of local estrogen hormone in improving the OAB symptoms in postmenopausal women with GSM. PATIENTS AND METHODS: A randomized, double-blind, placebo-controlled was carried out on 56 patients with GSM with the complaints consistent with OAB and recruited from the urogynecology out-patient clinic, Department of obstetrics and gynecology at El Shatby Alexandria University Hospital. Patients were divided into two groups: Group (A) received 0.5 g of conjugated estrogen (Premarin vaginal cream) twice weekly for 8 weeks, and group (B) received a placebo at the same dose. All subjects were subjected to full history taking, questionnaire derived from the UDI-6 and IIQ-7, clinical examination and investigations including complete urine analysis and urodynamic studies. After 8 weeks, patients in both groups were assessed again by a UDI-6 and IIQ-7 and urodynamics, and the results of both groups were compared. | ||||
Keywords | ||||
Overactive bladder; ESTROGEN; postmenopausal women | ||||
Supplementary Files
|
||||
Statistics Article View: 62 |
||||