Warts as a Therapeutic Dilemma; Different Therapies with focus on Intralesional Acyclovir and Intralesional Hepatitis-b Virus Vaccine
Ismail, A., Imam, M., Gharib, K. (2024). Warts as a Therapeutic Dilemma; Different Therapies with focus on Intralesional Acyclovir and Intralesional Hepatitis-b Virus Vaccine. EKB Journal Management System, 30(1), 262-270. doi: 10.21608/zumj.2023.177931.2691
Aya Taha Ismail; Mona Elradi Imam; Khaled Mohamed Gharib. "Warts as a Therapeutic Dilemma; Different Therapies with focus on Intralesional Acyclovir and Intralesional Hepatitis-b Virus Vaccine". EKB Journal Management System, 30, 1, 2024, 262-270. doi: 10.21608/zumj.2023.177931.2691
Ismail, A., Imam, M., Gharib, K. (2024). 'Warts as a Therapeutic Dilemma; Different Therapies with focus on Intralesional Acyclovir and Intralesional Hepatitis-b Virus Vaccine', EKB Journal Management System, 30(1), pp. 262-270. doi: 10.21608/zumj.2023.177931.2691
Ismail, A., Imam, M., Gharib, K. Warts as a Therapeutic Dilemma; Different Therapies with focus on Intralesional Acyclovir and Intralesional Hepatitis-b Virus Vaccine. EKB Journal Management System, 2024; 30(1): 262-270. doi: 10.21608/zumj.2023.177931.2691

Warts as a Therapeutic Dilemma; Different Therapies with focus on Intralesional Acyclovir and Intralesional Hepatitis-b Virus Vaccine

Zagazig University Medical Journal
Article 27, Volume 30, Issue 1, January and February 2024, Page 262-270  XML PDF (955.07 K)
Document Type: Review Articles
DOI: 10.21608/zumj.2023.177931.2691
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Authors
Aya Taha Ismail email 1; Mona Elradi Imam2; Khaled Mohamed Gharib3
1Department of Dermatology, Venereology, and Andrology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
2Dermatology and venereology Dept., Faculty of medicine, Zagazig University, Zagazig, Egypt
3Department of Dermatology,Venereology, and Andrology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Abstract
Warts are widespread epidermal growths caused by diverse strains of human papillomavirus (HPV) that affect all age groups. As in the case of palmoplantar warts, they are typically asymptomatic and unattractive, but occasionally painful. In spite of treatment, recalcitrant warts grow in size and number and are resistant to standard therapeutic approaches. Vaccine and antigen therapy are assumed to work by stimulating the host immune system into recognizing the virus, which leads to the removal of warts that is known as intralesional immunotherapy.
Vaccination against Hepatitis B virus (HBV) is linked to the induction of humoral and cell-mediated immunity. Recent use of intralesional HBV vaccination as an immunotherapy for common warts has been relatively unsuccessful.
The viral etiology of warts implies that acyclovir, an antiviral medication with demonstrated efficacy against DNA viruses, may be a viable treatment option.
This literature review aimed to discuss the comparative efficacy of intralesional HBV vaccination and acyclovir in treating plantar warts.
Keywords
Warts; immunotherapy; intralesional, HBV vaccine; acyclovir
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