Pomegranates bioactive metabolites and biological activities: an updated review
Abdelkarim, M., Ebrahim, A., Eissa, M., Ali, M., Shaban, A., Ahmed, A., Hassan, M., Ahmed, A., Eltayeb, K., Ahmed, O., Mohamed, A., Abdelsalam, M., Elsheikh, A., Mostafa, K., Said, S., Mohamed, S., Ali, A., Mohamed, S., Mahmoud, A., Moaaz, A., Mekky, R., Elgindi, O. (2023). Pomegranates bioactive metabolites and biological activities: an updated review. EKB Journal Management System, 2(1), 121-160. doi: 10.21608/erurj.2023.283010
Mahmoud Osama Abdelkarim; Abdallah Mahmoud Ebrahim; Moamen Morad Fathy Eissa; Moaz Essam Ali; Ahmed Lamaey Shaban; Abdelaty Mohamed Ahmed; Mohamed Mahmoud Hassan; Ahmed Abdelfattah Ahmed; Karim Kamal Eltayeb; Omar Ali Ahmed; Ali Ahsraf Mohamed; Mohamed Wael Abdelsalam; Alaa Gamal Elsheikh; Khaled Mohamed Mostafa; Said Basuony Said; Sara Ismail Mohamed; Aya Hussein Ali; Shrouk Ahmed Mohamed; Ahmed Nasr Eldin Mahmoud; Abdelrahman Faik Moaaz; Reham Hassan Mekky; Omayma Elgindi. "Pomegranates bioactive metabolites and biological activities: an updated review". EKB Journal Management System, 2, 1, 2023, 121-160. doi: 10.21608/erurj.2023.283010
Abdelkarim, M., Ebrahim, A., Eissa, M., Ali, M., Shaban, A., Ahmed, A., Hassan, M., Ahmed, A., Eltayeb, K., Ahmed, O., Mohamed, A., Abdelsalam, M., Elsheikh, A., Mostafa, K., Said, S., Mohamed, S., Ali, A., Mohamed, S., Mahmoud, A., Moaaz, A., Mekky, R., Elgindi, O. (2023). 'Pomegranates bioactive metabolites and biological activities: an updated review', EKB Journal Management System, 2(1), pp. 121-160. doi: 10.21608/erurj.2023.283010
Abdelkarim, M., Ebrahim, A., Eissa, M., Ali, M., Shaban, A., Ahmed, A., Hassan, M., Ahmed, A., Eltayeb, K., Ahmed, O., Mohamed, A., Abdelsalam, M., Elsheikh, A., Mostafa, K., Said, S., Mohamed, S., Ali, A., Mohamed, S., Mahmoud, A., Moaaz, A., Mekky, R., Elgindi, O. Pomegranates bioactive metabolites and biological activities: an updated review. EKB Journal Management System, 2023; 2(1): 121-160. doi: 10.21608/erurj.2023.283010

Pomegranates bioactive metabolites and biological activities: an updated review

ERU Research Journal
Article 4, Volume 2, Issue 1, January 2023, Page 121-160  XML PDF (889.16 K)
Document Type: Review article
DOI: 10.21608/erurj.2023.283010
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Authors
Mahmoud Osama Abdelkarim1; Abdallah Mahmoud Ebrahim1; Moamen Morad Fathy Eissa1; Moaz Essam Ali1; Ahmed Lamaey Shaban1; Abdelaty Mohamed Ahmed1; Mohamed Mahmoud Hassan1; Ahmed Abdelfattah Ahmed1; Karim Kamal Eltayeb1; Omar Ali Ahmed1; Ali Ahsraf Mohamed1; Mohamed Wael Abdelsalam1; Alaa Gamal Elsheikh1; Khaled Mohamed Mostafa1; Said Basuony Said1; Sara Ismail Mohamed1; Aya Hussein Ali1; Shrouk Ahmed Mohamed1; Ahmed Nasr Eldin Mahmoud1; Abdelrahman Faik Moaaz1; Reham Hassan Mekky email orcid 2; Omayma Elgindi2
1Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt
2Pharmacognosy Department, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt
Abstract
Pomegranate (Punica granatum L.) is a fruit that is widely consumed as fresh fruit and juice. The use of pomegranate fruit dates from ancient times and literature about its therapeutic qualities has echoed throughout the ages. Several in vitro and in vivo studies have shown how this fruit acts as antioxidant, antidiabetic, and hypolipidemic and shows antibacterial, antiparasitic antifungal, anti-inflammatory, antiviral, and anti-carcinogenic activities. The fruit also potentiates cardiovascular and oral health. These beneficial physiological effects may also have preventive applications in a variety of diseases such as (renal and hepatic toxicity). The health benefits of pomegranate have been attributed to its wide range of chemicals and extracts, which are predominantly polyphenols, including primarily hydrolysable ellagitannins, anthocyanins, sugars, organic acids and other polyphenols. The aim of this review is to present an updated overview of the functional, medical, chemical and physiological properties of this fruit and / or its agri-food residues.
Keywords
Pomegranate; polyphenols; ellagitannin, anthocyanins, agri-food residue
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