Does the price matter? potency comparative study for different Ceftriaxone generics in the Egyptian market | ||||
ERU Research Journal | ||||
Article 7, Volume 2, Issue 1, January 2023, Page 210-218 PDF (432.98 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/erurj.2023.188589.1007 | ||||
View on SCiNiTO | ||||
Authors | ||||
Mohamed Taha abdelaziz 1; Nagwa Osama Mohamed1; Ahmed Mohamed ElKhatib1; Yehia Abdelmoniem Mahmoud1; Marah Moustafa Hussein1; Esraa Korayem Hassan1; Amira Gamal Saad1; Dalia Ali El-dammasy1; Sara Wafdy Azmy2; Amira Mohamed Elsayed3; Ahmed Adel Elsayed2; Sarah Hussein Abdel Aal2; Tasnim Mohammed Abdelhamid2; Kholoud Farag Mohamed2; Fady Namr Ishak2; Amira Adel Elsayed2; Ziad Yasser Elsaied2; Aya Mohamed Ali2; Yara Hany Ghrseldin3; Ahmed Sheref Amer3; Mark Asaad Mahrous3; Hager Abdelkader Ibrahim3; Habiba Hany Hamed3; Mariam Mohammad Mostafa2; Norhan Sobhy Gamel2; Noura Elsayed Khalil2; Shahd Hany Ibrahim2; Nada Medhat Ibrahim2; Hanan Hatem Abdelmotalb2; Maria Mounir Mina2; Abdallah Ahmed Hosni3; Hanaa Mahmoud Khalifa2; Hadir Shaaban3; Ahmed Mounir Ibrahim3; Mohamed Ashraf Elshahedy3; Mohamed Ahmed Abdelkader3; Fatma Elzahraa ElBadrawy3; Nada Elaraby Ghareeb2; Tasneem Hussein Nagy2; Wesam Saeed Mohamed2; Ibrahiem Abdelrahman3; Tharwat El-khamissy1 | ||||
1Microbiology and Immunology Department, Egyptian-Russian University, Badr City, Egypt | ||||
2Clinical PharmD program, Faculty of Pharmacy, Egyptian-Russian University, Badr City, Egypt | ||||
3PharmD program, Faculty of Pharmacy, Egyptian-Russian University, Badr City, Egypt | ||||
Abstract | ||||
There are a lot of ceftriaxone sodium generics in the Egyptian market with a huge variation in prices, this raises a tremendous question mark, does the difference in prices reflect a difference in potency? So, we made a small-scale experiment to test generics potencies using the antibiotic agar diffusion method similar to the antibiotic assay method with its graphical and mathematical calculations. This experiment was in a form of a comparative study of ten ceftriaxone sodium generics in the Egyptian market using antibiotic agar diffusion against a standard strain of Staphylococcus aureus ATCC 977 as evaluator microorganism to test the antimicrobial effect of each generic by measuring Inhibition zone diameter (IZD) they leave on pre-inoculated agar plates; Considering the highest priced generic we purchased from the Egyptian market, which was generic A as a reference substitute for pure ceftriaxone sodium which couldn’t be afforded in this study. Our results revealed that there was a significant difference in potency, but curiously those differences were not correlated to the prices of the generics. | ||||
Keywords | ||||
Ceftriaxone sodium; Antibiotic resistance; Egyptian market; antibiotic agar diffusion method; potency comparison | ||||
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