‎Clinical and laboratory predictors of disease severity and outcome in ‎COVID 19 infected patients in Suez Canal University Hospital, single ‎center study from Egypt
Awd, K., Elnemr, N., Aboelmagd, M., Eida, M., Attia, F., Salama, B. (2023). ‎Clinical and laboratory predictors of disease severity and outcome in ‎COVID 19 infected patients in Suez Canal University Hospital, single ‎center study from Egypt. EKB Journal Management System, 4(2), 370-382. doi: 10.21608/mid.2023.184185.1441
kholoud Awd; Nader Elnemr; Mohamed Ahmed Aboelmagd; Mohamed Mohamed Eida; Fadia Mostafa Attia; Bassam Mansour Salama. "‎Clinical and laboratory predictors of disease severity and outcome in ‎COVID 19 infected patients in Suez Canal University Hospital, single ‎center study from Egypt". EKB Journal Management System, 4, 2, 2023, 370-382. doi: 10.21608/mid.2023.184185.1441
Awd, K., Elnemr, N., Aboelmagd, M., Eida, M., Attia, F., Salama, B. (2023). '‎Clinical and laboratory predictors of disease severity and outcome in ‎COVID 19 infected patients in Suez Canal University Hospital, single ‎center study from Egypt', EKB Journal Management System, 4(2), pp. 370-382. doi: 10.21608/mid.2023.184185.1441
Awd, K., Elnemr, N., Aboelmagd, M., Eida, M., Attia, F., Salama, B. ‎Clinical and laboratory predictors of disease severity and outcome in ‎COVID 19 infected patients in Suez Canal University Hospital, single ‎center study from Egypt. EKB Journal Management System, 2023; 4(2): 370-382. doi: 10.21608/mid.2023.184185.1441

‎Clinical and laboratory predictors of disease severity and outcome in ‎COVID 19 infected patients in Suez Canal University Hospital, single ‎center study from Egypt

Microbes and Infectious Diseases
Article 5, Volume 4, Issue 2, May 2023, Page 370-382  XML PDF (1.06 MB)
Document Type: Original Article
DOI: 10.21608/mid.2023.184185.1441
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Authors
kholoud Awd1; Nader Elnemr1; Mohamed Ahmed Aboelmagdorcid 1; Mohamed Mohamed Eida1; Fadia Mostafa Attia2; Bassam Mansour Salama email orcid 1
1Infection and endemic disease department, faculty of medicine, Suez Canal University, Ismailia, Egypt
2Clinical Pathology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
Abstract
Background: The novel corona virus is a high contagious disease, ‎declared by World Health Organization (WHO) as a global pandemic in 2020 with profound ‎impact on morbidity and mortality, assessment of outcomes in infected patients and ‎knowledge of prediction of mortality and morbidity are important. We aimed to assess ‎the clinical and laboratory findings in predicting COVID-19 severity and outcome in ‎patients admitted to Suez Canal University Teaching Hospital.‎ Methodology: This cross-sectional prospective study included 500 ‎confirmed PCR COVID-19 infected patients, selected through random sampling‎. A ‎structured checklist was used to collect patient data.‎ Results: Mean age was 61.8 years, 56.2% were males, 74.8% had ‎comorbidities. Lung involvement was evident in more than 75% on CT, 17.2% had ‎leukopenia, 42.2% had lymphocytopenia between 5 – 10% and 93% of the patients ‎had elevated neutrophil- lymphocyte ratio. 65.8% had elevated D-dimer, and elevated ‎liver and kidney functions were found in 40.6% and 25% respectively. The mortality ‎rate in studied population was 30.2% and it was significantly associated with old age, ‎hypoxemia, having high involvement of the lungs on CT. Decreased WBC count, ‎high D-dimer level and high NLR associated with severity and increased death rate of ‎the disease.‎ Conclusion: The study revealed many findings with impact on the patient's severity and outcome old age, laboratory findings, CT imaging and need to antiviral therapy the most predicting factors of the ‎severity and prognosis of the patients.
Keywords
COVID-19; predictors; severity; outcome; Egypt‎
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