CRISPR in dentistry: A boon or bane | ||||
| Microbes and Infectious Diseases | ||||
| Article 15, Volume 4, Issue 4, November 2023, Page 1178-1182 PDF (750.4 K) | ||||
| Document Type: Mini-review article | ||||
| DOI: 10.21608/mid.2023.188121.1453 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Mirna Garhnayak1; Shakti Rath  2; Loknath Garhnayak3; Sangram Panda4
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| 1Professor, Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar 751003, Odisha, India. | ||||
| 2Central Research Laboratory, Institute of Dental Sciences, Siksha O Anusandhan Deemed to be University, Bhubaneswar, Odisha | ||||
| 3Professor, Department of Prosthodontics and Crown and Bridge, SCB Dental College and Hospital, Cuttack 753007, Odisha, India | ||||
| 4Professor, Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar 751003, Odisha, India | ||||
| Abstract | ||||
| Background: Clustered Regularly Inter Spaced Palindromic Repeats (CRISPR) is programmable protein that can change the genome's content, remove it, and switch it on and off. This cutting-edge technology offers a wide range of uses and has the potential to change the future of oral health. Because of its efficacy and precision, the CRISPR-associated protein 9 (Cas9) genome editing technology could be a promising therapeutic tool in the treatment of oral cancer. It quickly changes the genetic makeup of cell lines, organs, and animals. As a result, gene editing has expanded to include genome-wide screening for both loss and augmentation of function. The CRISPR-Cas9 genome editing method and its uses in dentistry have been summarised in this study. | ||||
| Keywords | ||||
| Oral Diseases; CRISPR; Cas9; genome editing; Dentistry | ||||
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