Pattern and Outcome of Acute Aluminium Phosphide Intoxicated Cases at Sohag University Hospitals: Special Consideration to Paraffin Oil as a Supportive Treatment | ||||
| Zagazig Journal of Forensic Medicine | ||||
| Article 8, Volume 21, Issue 1, January 2023, Page 133-156 PDF (736.42 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zjfm.2023.180421.1133 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Mai Abdelkader  1; Reda Elsayed2; Meray Medhat Shokry3
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| 1forensic medicine and clinical toxicology, faculty of medicine, sohage university, sohage | ||||
| 2department of forensic medicine and clinical toxicology, faculty of medicine, Sohag university | ||||
| 3Department of forensic medicine and clinical toxicology, faculty of medicine Sohag university | ||||
| Abstract | ||||
| Introduction: In the last years poisoning by aluminium phosphide (AlP) became a common method of suicide with high mortality rates. Aim of the work: The study aimed to evaluate the characters and outcome of acute aluminum phosphide intoxicated cases at Sohag university hospitals. Patients and methods: It is a cross sectional study conducted on acutely AlP intoxicated patients attended Sohag university hospitals including a retrospective part from January 2020 to December 2021(23 case) and a prospective part from January 2022 to June 2022 (41 case). Demographic data, mode of poisoning, route of administration, amount taken, delay time, vital signs, degree of coma, ejection fraction, troponin I and creatinine levels and first aid measures were recorded then related them to the patient outcome. Results: the incidence of ALP toxicity increased every year, in 2020 was 10.9%, in 2021 (25%), while, in the first half of 2022 it was 64.1%. The mean age was 21.7± 10.65 with male predominance by 53.1%. There was a significant increase in percentage of survived patients decontaminated by paraffin oil (84.6%) compared to other methods (15.4%). Receiver operating characteristic curve (ROC) was used to assess predictors of mortality in acute ALP-poisoned patients. The accuracy rate of ejection fraction, poisoning severity score (PSS), dose, serum troponin I, systolic blood pressure, delay time, and HCO3 were 100%, 97.7%, 94.4%, 93.7%, 89.5%, 81.9%, and 80.1% respectively with excellent discrimination. Diastolic blood pressure (77.9%) and PH (75.2%) with acceptable discrimination. While, creatinine and GCS gave non-acceptable discrimination. Conclusion: the frequency of suicidal ingestion of ALP is increasing every year. Decontamination by paraffin oil and early presentation had a better prognosis. At admission assessment of ejection fraction, PSS, serum troponin and creatinine, blood pressure, ABG have a beneficial role as predictors of mortality and emergency intervention to cases with probable bad prognosis. | ||||
| Keywords | ||||
| Key words: Aluminum phosphide; poisoning pattern; paraffin oil; outcome; mortality predictors | ||||
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