WOUND HEALING PROPERTIES OF GREEN TEA EXTRACT IN EXCISION-WOUNDED RATS | ||||
Al-Azhar Journal of Pharmaceutical Sciences | ||||
Article 9, Volume 56, Issue 2, September and October 2017, Page 102-114 PDF (597.78 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ajps.2017.28464 | ||||
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Author | ||||
alaa Shahein | ||||
Abstract | ||||
The wound healing potential of green tea extract (GTE) was determined in two concentrations (0.6 and 6% in Vaseline base) for topical treatment of excision wounds in rats. Treatments were applied for 14 days. GTE, in both concentrations, caused a significant increase in wound contraction rate and glutathione level, as well as a significant decrease in lipid peroxidation and transforming growth factor-β expression. Moreover, histological examination showed a marked improvement in the skin condition. This study concludes that GTE was effective in enhancing the healing process in excision wounds. | ||||
Keywords | ||||
green tea; Wound healing; Oxidative Stress | ||||
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