The Effect of Abdominal Contouring on Metabolic syndrome and Insulin Resistance | ||||
| The Egyptian Journal of Plastic and Reconstructive Surgery | ||||
| Articles in Press, Accepted Manuscript, Available Online from 12 February 2023 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejprs.2023.187011.1254 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Abraham Hosny Shawky   1; Nesma Hussien Ahmed2; Ahmed Mohammed Abdelsalam3; salah nasser mohammed afifi4; Mohamed Samir Badawy 5
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| 1Department of Plastic, Burn & Maxillofacial Surgery department, Faculty of Medicine - Ain Shams University, Cairo, Egypt | ||||
| 2**Department of Internal Medicine, Endocrinology &Metabolism. Faculty of Medicine - Ain Shams University | ||||
| 3Department of Plastic, Burn & Maxillofacial Surgery, Faculty of Medicine - Ain Shams University, Cairo, Egypt | ||||
| 4professor of plastic,burn and maxillofacial surgery ,ain shams university | ||||
| 5*Department of Plastic, Burn and Maxillofacial Surgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt | ||||
| Abstract | ||||
| ABSTRACT Background: The deep layers of abdominal subcutaneous adipose tissue (SAT) behave functionally like the visceral adipose tissue (VAT). Both aggravate insulin resistance and affect the metabolic profile in a similar manner. So, the removal of Abdominal subcutaneous tissue in abdominal contouring surgeries as liposuction and lipo-abdominoplasty can positively affect insulin resistance and the metabolic profile. Patients and Methods: 50 female patients with localized abdominal obesity i.e. skin pinch ≥ 3 cm, Metabolic syndrome i.e. three or more of the following criteria: (waist circumference ≥35 inches, waist-hip ratio above 0.85, blood pressure ≥ 130/85 mmHg, fasting triglyceride (TG) level ≥ 150 mg/dl, fasting high-density lipoprotein (HDL) cholesterol level ≤ 50 mg/dl and fasting blood sugar ≥ 100 mg/dl) and insulin resistance i.e. fasting glucose ≥ l00 mg/dL, 2-hour plasma glucose ≥140 mg/dl, fasting insulin level ≥ 5 µIU/mL and HbA1C between 5.7-6.4%. Patients were divided into two groups, Group І (n=25); the lipo-abdominoplasty group and Group ІІ (n=25); the liposuction only group. The change in the metabolic profile and insulin resistance was followed 3- and 6-months post operatively by measuring waist circumference, waist-hip ratio, blood pressure, fasting triglyceride, fasting high-density lipoprotein (HDL) cholesterol level, fasting blood sugar, fasting insulin, and fasting glucose level using specific laboratory equation called Homeostasis Model Assessment (HOMA-IR). Results: For both groups, there is a significant improvement in glycemic and lipid profile for all studied patients together with weight loss and BMI. but there was no difference in glycemic or lipid profile between both groups. Waist/hip ratio was significantly improved in lipo-abdominoplasty group more than liposuction only group. There was no relation between amount of resected fat and the improvement in glycemic and lipid profile for all patients. Conclusion: As a part of body contouring surgeries, Liposuction and lipo-abdominoplasty could play a role in improvement of insulin resistance and metabolic syndrome in patients with localized abdominal obesity. So, one time, it may not only be considered as an aesthetic procedure to improve the individual body image, but also it can be approved by the authorities and insurance companies as it affects the wellbeing. | ||||
| Keywords | ||||
| Keywords: Abdominoplasty; Liposuction; fat; Obesity; Metabolic profile | ||||
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