Estimation of Leptin and Estrogen Hormones in Obese Women with Arthritis
Jabbar, M., Khudair Hussein, Z. (2023). Estimation of Leptin and Estrogen Hormones in Obese Women with Arthritis. EKB Journal Management System, 90(2), 2709-2715. doi: 10.21608/ejhm.2023.286433
Maryam Abdul Hussein Jabbar; Zainab Khudair Hussein. "Estimation of Leptin and Estrogen Hormones in Obese Women with Arthritis". EKB Journal Management System, 90, 2, 2023, 2709-2715. doi: 10.21608/ejhm.2023.286433
Jabbar, M., Khudair Hussein, Z. (2023). 'Estimation of Leptin and Estrogen Hormones in Obese Women with Arthritis', EKB Journal Management System, 90(2), pp. 2709-2715. doi: 10.21608/ejhm.2023.286433
Jabbar, M., Khudair Hussein, Z. Estimation of Leptin and Estrogen Hormones in Obese Women with Arthritis. EKB Journal Management System, 2023; 90(2): 2709-2715. doi: 10.21608/ejhm.2023.286433

Estimation of Leptin and Estrogen Hormones in Obese Women with Arthritis

The Egyptian Journal of Hospital Medicine
Article 108, Volume 90, Issue 2, January 2023, Page 2709-2715  XML PDF (942.79 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2023.286433
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Authors
Maryam Abdul Hussein Jabbar email ; Zainab Khudair Hussein
Abstract
Background: Obesity is abnormal accumulation of fat in the body, which led to many health problems that will reduce the life expectancy. Arthritis is joints inflammation that cause many of symptoms such as swelling, tenderness, pain and stiffness of most joints. The arthritis is divided into many types, but the most common types are osteoarthritis and rheumatoid arthritis the last type is the focus of our topic. Rheumatoid arthritis (RA) is an auto-immune, chronic inflammation that can cause damage for joints and other body organs like skin, eyes, lungs, heart and blood vessels.
Objective: The study aimed to investigate the levels of leptin and estrogen hormones in obese women with arthritis. We focused on rheumatoid arthritis especially.
Patients and Methods: The research included ninety women They were distributed into three groups, 30 obese women with body mass index (BMI) more than 25 Kg/m2 for overweight and more than 30 Kg/  for obese, 30 obese women with rheumatoid arthritis which have positive rheumatoid factor (RF) and 30 control women with normal weight and BMI < 25Kg/  and healthy from RA. BMI, WHR was calculated for all participants.
Result: The result of estrogen hormone showed highly significant difference (P≤0.01) in G1 (55.74 ± 9.23), G2 (55.35 ± 11.77) compared to G3 (129.85 ±16.69). While leptin hormone revealed no significant difference among G1 (2102.13 ±78.03), G2 (2005.80 ±23.81) and G3 (1931.27 ±22.91).
Conclusion: We concluded that leptin levels did not differ among the three groups. Conversely estrogen levels showed highly difference between the three groups.
 
Keywords
Obesity; Body mass index; Waist-hips ratio; Rheumatoid arthritis; Leptin; Estrogen hormones
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