Combined Use Of MRI Morphological Criteria And Apparent Diffusion Coefficient (ADC value) In Diagnosis Of Probably Benign and Suspicious Breast Lesions (BI-RADS3 and 4) in Correlation with Histopathology
Wagih, A., Abd Elraheem, S., Abdelgawad, E., Hussein, N. (2023). Combined Use Of MRI Morphological Criteria And Apparent Diffusion Coefficient (ADC value) In Diagnosis Of Probably Benign and Suspicious Breast Lesions (BI-RADS3 and 4) in Correlation with Histopathology. EKB Journal Management System, (), -. doi: 10.21608/mjmr.2023.187065.1297
Alaa Wagih; Sara Mohammed Abd Elraheem; Ehab Ali Abdelgawad; Nada Hussein. "Combined Use Of MRI Morphological Criteria And Apparent Diffusion Coefficient (ADC value) In Diagnosis Of Probably Benign and Suspicious Breast Lesions (BI-RADS3 and 4) in Correlation with Histopathology". EKB Journal Management System, , , 2023, -. doi: 10.21608/mjmr.2023.187065.1297
Wagih, A., Abd Elraheem, S., Abdelgawad, E., Hussein, N. (2023). 'Combined Use Of MRI Morphological Criteria And Apparent Diffusion Coefficient (ADC value) In Diagnosis Of Probably Benign and Suspicious Breast Lesions (BI-RADS3 and 4) in Correlation with Histopathology', EKB Journal Management System, (), pp. -. doi: 10.21608/mjmr.2023.187065.1297
Wagih, A., Abd Elraheem, S., Abdelgawad, E., Hussein, N. Combined Use Of MRI Morphological Criteria And Apparent Diffusion Coefficient (ADC value) In Diagnosis Of Probably Benign and Suspicious Breast Lesions (BI-RADS3 and 4) in Correlation with Histopathology. EKB Journal Management System, 2023; (): -. doi: 10.21608/mjmr.2023.187065.1297

Combined Use Of MRI Morphological Criteria And Apparent Diffusion Coefficient (ADC value) In Diagnosis Of Probably Benign and Suspicious Breast Lesions (BI-RADS3 and 4) in Correlation with Histopathology

Minia Journal of Medical Research
Articles in Press, Accepted Manuscript, Available Online from 20 February 2023  XML
Document Type: Original Article
DOI: 10.21608/mjmr.2023.187065.1297
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Authors
Alaa Wagih1; Sara Mohammed Abd Elraheem email 2; Ehab Ali Abdelgawadorcid 3; Nada Hussein4
1radiology department, faculty of medicine, minia university
2كلية الطب البشرى قسم الأشعة التشخيصية
3Radiology department, faculty of medicine, Minia University
4Department of clinical oncology
Abstract
Background: This prospective clinical study is aimed to evaluate the diagnostic value of morphological criteria, the apparent diffusion coefficient (ADC) and diffusion-weighted imaging in differentiating benign from malignant breast lesions in correlation with histopathology.

Method: The study includes 25 females with 25 breast lesions. Routine conventional MRI protocol of the breast was conducted including T2WI, T2 SPAIR and DWI. We used contrast administration in only 10 patients of this study group and DCE-MRI was conducted on them. We compared the conventional unenhanced images to the DCE-MRI by radiologists to detect and characterize breast lesions then we compared the results with the final reference diagnoses supplied by the histopathology. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy for UE-MRI and DCE-MRI were calculated.

Results: The calculated UE-MRI sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were 100%, 85.7%, 94.7%, 100%, and 96% respectively. On the other hand, those for the DCE-MRI were 100%, 75%, 85.7%, 100%, and 90% respectively.

Conclusion: The unenhanced MRI of the breast can be an available, reliable, and effective alternative for breast DCE-MRI. Also it can be used with comparable accuracy to DCE-MRI when contrast administration is not suitable or contraindicated.
Keywords
Diffusion weighted imaging; Unenhanced MRI; the Breast Imaging Reporting and Data System; morphology and dynamic contrast enhancement
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