Evaluation of Sentinel Lymph Node Mapping in Uterine Cancer Staging | ||||
| Suez Canal University Medical Journal | ||||
| Article 8, Volume 26, Issue 1, January 2023, Page 70-75 PDF (355.69 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/scumj.2023.287284 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Hamada Fathy; Mahmoud Hussin  ; Ahmed AboBakr; Solimam El-Kammash; Ahmed M. Gomaa
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| Department of Surgery, Faculty of Medicine, Suez Canal University, Ismailia, Egypt | ||||
| Abstract | ||||
| Background: Lymphatic mapping recently emerged as a promising new strategy and is increasingly being adopted by gynecologic oncology practices worldwide. The sentinel lymph node is a technique used to properly detect nodal metastases hence improving staging accuracy with the subsequent proper application of adjuvant therapy. Aim: to evaluate of the accuracy of sentinel lymph node biopsy using a patant blue dye in endometrial and cervical malignancies. Patients and Methods: Twenty-six patients, diagnosed with endometrial cancers stage (I/II) by MRI, and three patients, diagnosed with cervical cancers stage (Ia/IIa) by MRI, were enrolled in the study. Results: Sentinel lymph node(s) were successfully identified in 18 patients (69.2%) with endometrial carcinoma and one case with cancer cervix. The sensitivity of sentinel Lymph node mapping in the detection of lymph node metastasis was 100% with a negative predictive value of 100% and 0% false negative rate. There was a statistically significant inverse relation between sentinel lymph node detection and tumor grading. There was a statistically significant relation between sentinel lymph node detection and both cervical involvement and positive lymph node metastasis. Conclusion: Sentinel Lymph node mapping in cases of early-stage endometrial cancer is a good option to avoid overtreatment with unnecessary removal of more lymph nodes, which may result in an increase in perioperative adverse effects. | ||||
| Keywords | ||||
| Sentinel Lymph Node; Lymphatic Mapping; Endometrial Carcinoma; Cancer cervix | ||||
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