Seroprevalence of Helicobacter pylori infection and risk factors among patients presenting with symptoms of peptic ulcer in Akure metropolis
Abbah, P., ADEBOLU, T., Oladejo, B. (2023). Seroprevalence of Helicobacter pylori infection and risk factors among patients presenting with symptoms of peptic ulcer in Akure metropolis. EKB Journal Management System, 4(4), 1296-1306. doi: 10.21608/mid.2023.192688.1465
Patience Iye Abbah; TINUOLA TOKUNBO ADEBOLU; Babayemi Olawale Oladejo. "Seroprevalence of Helicobacter pylori infection and risk factors among patients presenting with symptoms of peptic ulcer in Akure metropolis". EKB Journal Management System, 4, 4, 2023, 1296-1306. doi: 10.21608/mid.2023.192688.1465
Abbah, P., ADEBOLU, T., Oladejo, B. (2023). 'Seroprevalence of Helicobacter pylori infection and risk factors among patients presenting with symptoms of peptic ulcer in Akure metropolis', EKB Journal Management System, 4(4), pp. 1296-1306. doi: 10.21608/mid.2023.192688.1465
Abbah, P., ADEBOLU, T., Oladejo, B. Seroprevalence of Helicobacter pylori infection and risk factors among patients presenting with symptoms of peptic ulcer in Akure metropolis. EKB Journal Management System, 2023; 4(4): 1296-1306. doi: 10.21608/mid.2023.192688.1465

Seroprevalence of Helicobacter pylori infection and risk factors among patients presenting with symptoms of peptic ulcer in Akure metropolis

Microbes and Infectious Diseases
Article 27, Volume 4, Issue 4, November 2023, Page 1296-1306  XML PDF (835.36 K)
Document Type: Original Article
DOI: 10.21608/mid.2023.192688.1465
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Authors
Patience Iye Abbah email orcid 1; TINUOLA TOKUNBO ADEBOLU2; Babayemi Olawale Oladejo3
1Microbiology, Department of Life Science, Federal University of Technology, Akure, Nigeria
2DEPARTMENT OF MICROBIOLOGY, FEDERAL UNIVERSITY OF TECHNOLOGY , AKURE, NIGERIA
3Department of Microbiology, Federal University of Technology, Akure, Nigeria
Abstract
Background: Helicobacter pylori (H. pylori) is a causative agent of peptic ulcer which presently affects more than half of the world's population. This study determined H. pylori prevalence and risk variables among peptic ulcer patients in Akure, Ondo State, Nigeria. Methods: Two-hundred (200) study participants consented at local hospitals. A pre-tested, structured questionnaire collected socio-demographic and risk factor information from participants. Participants' blood samples were tested with a fast chromatographic immunoassay kit for H. pylori antibodies. Results: 73.5 %of the 200 tested subjects had H. pylori. Prevalence was greater among women (74.8%) than men (71.6%). The most heavily impacted age group for H. pylori infection is 21–30 years with 78.4% prevalence, while the least affected is 51–60 years with 66.7% prevalence. Married respondents (77.2%) had a greater prevalence of H. pylori than singles (71.1%). The difference in prevalence rate based on individuals' education and occupation was not statistically significant (p=0.407 and 0.999, respectively). Helicobacter pylori infection was significantly associated with NSAID use (X2= 8.917, p=<0.001), smoking (X2=4.988, p=0.02), residing in a crowded room (X2=4.439, p=0.03), and a family history of peptic ulcer (X2=19.70, p=<0.0001). Conclusion: This study found substantial H. pylori prevalence among peptic ulcer patients. Helicobacter pylori testing should be considered relevant in clinical practice, especially in patients with peptic ulcer symptoms, and not only antacid prescriptions. For efficient patient treatment and to prevent chronic gastritis and stomach cancer, H. pylori must be thoroughly investigated and treated.
Keywords
Helicobacter pylori; seroprevalence; peptic ulcers; risk factors; asymptomatic
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