Evaluation of Serum Paraoxonase and Prolidase Levels in Patients with Premature Graying Of Hair

Wadie Mikhael, Nancy; Mohammed El Habak, Doaa; Adel El Fallah, Asmaa; Abbas Amin, Eman

doi:10.21608/bjas.2023.189462.1045

	Evaluation of Serum Paraoxonase and Prolidase Levels in Patients with Premature Graying Of Hair
Benha Journal of Applied Sciences
Article 20, Volume 8, Issue 2, February 2023, Page 35-41 PDF (447.38 K)
Document Type: Original Research Papers
DOI: 10.21608/bjas.2023.189462.1045
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Authors
Nancy Wadie Mikhael¹; Doaa Mohammed El Habak¹; Asmaa Adel El Fallah²; Eman Abbas Amin ¹
¹Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha University
²Clinical and Chemical Pathology Dept., Faculty of Medicine, Benha University
Abstract
Background: Premature greying of hair (PGH) is described as hair greying before the age of 20 in Caucasians, 25 in Asians, and 30 in blacks. This work aimed to evaluate demographic and clinical features of individuals with premature greying of the hair. Methods: This case-control study included 60 patients with PGH and 30 healthy controls of comparable age and gender. They were selected from the Outpatient Clinic of the Dermatology and Andrology Department at Benha University Hospital. Results: Statistically significant difference was seen among two groups of study concerning mean age and smoking distribution. Mean age of PGH onset among studied patients was 18.93 years (± 5.6 SD). The mean triglyceride and Cholesterol levels were moderately but not substantially higher in patients of PHG than controls. The mean HDL level considerably decreased among PGH patients than controls although the mean LDL level of PGH patients was substantially greater than that of controls. although the mean LDL level of PGH patients was substantially greater than that of controls. Comparing the proportion of people with low blood ferritin levels between the sick group (18.3 percent) and the control group (3.3 percent), a meaningful statistical difference was found. No substantial change in haemoglobin and VLDL concentrations among two groups. Conclusion: To elucidate the clinical and epidemiological features and linked reasons of PGH, there is a need for further epidemiological research on people of many ethnic backgrounds. Background: Premature greying of hair (PGH) is described as hair greying before the age of 20 in Caucasians, 25 in Asians, and 30 in blacks. This work aimed to evaluate demographic and clinical features of individuals with premature greying of the hair. Methods: This case-control study included 60 patients with PGH and 30 healthy controls of comparable age and gender. They were selected from the Outpatient Clinic of the Dermatology and Andrology Department at Benha University Hospital. Results: Statistically significant difference was seen among two groups of study concerning mean age and smoking distribution. Mean age of PGH onset among studied patients was 18.93 years (± 5.6 SD). The mean triglyceride and Cholesterol levels were moderately but not substantially higher in patients of PHG than controls. The mean HDL level considerably decreased among PGH patients than controls although the mean LDL level of PGH patients was substantially greater than that of controls. although the mean LDL level of PGH patients was substantially greater than that of controls. Comparing the proportion of people with low blood ferritin levels between the sick group (18.3 percent) and the control group (3.3 percent), a meaningful statistical difference was found. No substantial change in haemoglobin and VLDL concentrations among two groups. Conclusion: To elucidate the clinical and epidemiological features and linked reasons of PGH, there is a need for further epidemiological research on people of many ethnic backgrounds.
Keywords
Premature; Graying; Hair – PGH


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