Genetic Dissimilarity Adrenoceptor Alpha (ERa) in Hepatitis C virus-induced Cirrhosis and HCC
Amer, M., Elmetwalli, A., Attia, A., Hassan, A., Nasr Eldin, M. (2023). Genetic Dissimilarity Adrenoceptor Alpha (ERa) in Hepatitis C virus-induced Cirrhosis and HCC. EKB Journal Management System, 15(1), 61-66. doi: 10.21608/eajbsg.2023.288659
Mahmoud Amer; Alaa Elmetwalli; Attia A. Attia; Ayman Hassan; Mohamed A. Nasr Eldin. "Genetic Dissimilarity Adrenoceptor Alpha (ERa) in Hepatitis C virus-induced Cirrhosis and HCC". EKB Journal Management System, 15, 1, 2023, 61-66. doi: 10.21608/eajbsg.2023.288659
Amer, M., Elmetwalli, A., Attia, A., Hassan, A., Nasr Eldin, M. (2023). 'Genetic Dissimilarity Adrenoceptor Alpha (ERa) in Hepatitis C virus-induced Cirrhosis and HCC', EKB Journal Management System, 15(1), pp. 61-66. doi: 10.21608/eajbsg.2023.288659
Amer, M., Elmetwalli, A., Attia, A., Hassan, A., Nasr Eldin, M. Genetic Dissimilarity Adrenoceptor Alpha (ERa) in Hepatitis C virus-induced Cirrhosis and HCC. EKB Journal Management System, 2023; 15(1): 61-66. doi: 10.21608/eajbsg.2023.288659

Genetic Dissimilarity Adrenoceptor Alpha (ERa) in Hepatitis C virus-induced Cirrhosis and HCC

Egyptian Academic Journal of Biological Sciences, G. Microbiology
Volume 15, Issue 1, June 2023, Page 61-66  XML PDF (582.88 K)
Document Type: Original Article
DOI: 10.21608/eajbsg.2023.288659
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Authors
Mahmoud Amer1; Alaa Elmetwalli2; Attia A. Attia1; Ayman Hassan3; Mohamed A. Nasr Eldin1
1Botany and Microbiology Department, Faculty of Science, Benha University, Benha, Egypt.
2Department of Clinical Trial Research Unit and Drug Discovery, Egyptian Liver Research Institute and Hospital (ELRIAH), Mansoura, Egypt.
3Department of Medical Research and Diagnostic Labs, Egyptian Liver Research Institute and Hospital, Mansoura, Egypt
Abstract
Hepatocellular carcinoma (HCC), the fifth most common kind of cancer in the world, is a significant public health concern in Egypt. The development of HCC has been linked to genetic diversity, making the disease challenging to treat. The bulk of the chronic liver illnesses that 95% of HCC patients suffer started by viruses. HCC is a complicated condition. One of the origins of HCC is the hepatitis C virus (HCV). Though being branded to piece a part in a variety of biological courses and having evidence portentously together a carcinogenic and a preemptive influence on the liver, the importance of ERa in the expansion of HCC remains doubtful. It has been shown that those with HCV have a high level of ERa expression. This study reveals how ERa and its variants affect how hepatocarcinogenesis develops.
Keywords
Hepatocellular carcinoma (HCC)
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